Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (10 mg/ml), ethanol (15 mg/ml), methanol, choroform (25 mg/ml)
- Melting Point
- 150-153° C
- Optical Activity
- [α]20/D +76°, c = 0.5 in methanol
Category: Antibiotics
Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
Synonyms | Arteannuin, Qinghaosu, NSC 369397 |
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Purity | ≥95% (HPLC) |
Appearance | White powder |
CAS-Number | 63968-64-9 |
Molecular Formula | C15H22O5 |
Molecular Weight | 282.33 |
Identity | 1H-NMR |
Solvents | DMSO (10 mg/ml), ethanol (15 mg/ml), methanol, choroform (25 mg/ml) |
Melting Point | 150-153° C |
Optical Activity | [α]20/D +76°, c = 0.5 in methanol |
Smiles | CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C_x000D_ |
InChi Key | BLUAFEHZUWYNDE-NNWCWBAJSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Hazard statements | H242, H400, H410 |
Precautionary statements | P210, P220, P234, P273, P280, P370+P378, P391, P403+P235, P411, P420, and P501 |
GHS Symbol | GHS02+GHS09 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) A. Zyad, et al., Phytother. Res. 32, 216 (2018), (2) E. Konstat-Korzenny, et al., Med. Sci. 6, E19 (2018), (3) Y. Zhang, et al., Nat. Prod. Bioprospect. 8, 303 (2018), (4) A. Kumari, et al., Eur. J. Med. Chem. 163, 804 (2019) |
Quantity | 100 mg, Bulk |