Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform, DMSO
Category: Quorum Sensing
N-(3-Oxoundecanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
Synonyms | 3-oxo-C11-L-HSL, 3-oxo-N-[(3S)-2-oxooxolan-3-yl]undecanamide |
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Purity | ≥97% (HPLC) |
Appearance | White to off-white powder |
CAS-Number | 216596-70-2 |
Identity | 1H-NMR |
Solvents | chloroform, DMSO |
Smiles | O=C1[C@@H](NC(CC(CCCCCCCC)=O)=O)CCO1 |
InChi Key | SELZAQGRPYIEQS-ZDUSSCGKSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Hazard statements | H302 |
GHS Symbol | GHS07 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) S.R. Chhabra, et al., J. Med. chem. 46, 97 (2003), (2) J. Zhu, et al., Appl. Environ. Microbiol. 69, 6949 (2003), (3) C.L. Weingart, et al., Mol. Microbiol. 57, 452 (2005), (4) S.-A. Alexander, et al., Chem. Commun. 51, 3355 (2015) |
Quantity | 10 mg, 50 mg, Bulk |