Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (5 mg/ml)
Category: API's & Intermediates
Risperidone is a benzisoxazole derivative and serotonin-dopamine antagonist. It is an atypical antipsychotic that binds to dopamine D2 receptors (Ki=3nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki=0.12nM). It also binds to dopamine D4, α1- and α2-adrenergic, 5-HT1C, 5-HT1D, and histamine H1 receptors. It therefore functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Formulations containing risperidone have been used in the treatment of schizophrenia, autism and bipolar disorder.
Synonyms | R64766, Apexidone, Psychodal |
---|---|
Purity | ≥98% (HPLC) |
Appearance | White to off-white powder |
CAS-Number | 106266-06-2 |
Molecular Formula | C17H26N2O |
Molecular Weight | 410.48 |
Identity | 1H-NMR |
Solvents | DMSO (5 mg/ml) |
Smiles | CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F |
InChi Key | RAPZEAPATHNIPO-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | RT |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
GHS Symbol | GHS06 |
Signal word | Danger |
RIDADR | 2811 6.1 |
Transportation | Packing Group III |
References | (1) J.E. Leysen, et al., Mol. Pharmacol. 41, 494 (1992), (2) F.P. Bymaster, et al., Neuropsychopharmacol. 14, 87 (1996) |
Quantity | 10 mg, 50 mg, Bulk |