Available from stock

1,1′-Dibutyl-3,3,3′,3′-tetramethylindocarbocyanine iodide

SKU: D0224

Category: Fluorescent Detection

Synonyms: DiIC4(3); 132752-00-2
CAS-Number: C₃₁H₄₁N₂.I
Molecular Formula: 568.58
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Violett crystalline solid
Identity: 1H-NMR

Properties

Solvents: DMSO or methanol
Melting Point: 172-175 °C
Fluorescence: λex 506 nm; λem 578 nm in phosphate buffer/SDS pH 7.0

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and air. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315-H319-H335
Precautionary statements: P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: DiIC4(3) is a fluorescent carbocyanine dye with butyl chains widely used for membrane staining due to its hydrophobic nature, which helps it intercalate well into lipid bilayers. Carbocyanine dyes are unique organic molecules that contain a conjugated electron-deficient system between two heterocyclic nitrogen atoms that provides characteristically long absorption and emission wavelengths. It can be used for cell tracking as it is stably retained in membranes and in fixed tissue slices for anterograde and retrograde tracing. Spectral Data: Excitation max: ~550-555nm, Emission max: ~565-570nm (accord. Lit). Also used as intermediate for the synthesis of selective protein arginine methyltransferases (PRMT) inhibitors. Intermediate for the synthesis of fluorescent probes.
Smiles: CCCCN\1C2=CC=CC=C2C(/C1=C\C=C\C3=[N+](C4=CC=CC=C4C3(C)C)CCCC)(C)C.[I-]
InChi Key: CVTQMCMIKOZBTI-UHFFFAOYSA-M
References: (1) G. Suaerwein & G.B. Schuster, J. Phys. Chem. 95, 1903 (1991) , (2) G. Beckford, et al., Talanta 92, 45 (2012) , (3) S.H. Sinha, et al., Eur. J. Med. Chem. 54, 647 (2012) , (4) H. Hu, et al., J. Med. Chem. 58, 1228 (2015) , (5) M. Matsui, et al., Tetrahedron 71, 3528 (2015)
InChi: InChI=1S/C31H41N2.HI/c1-7-9-22-32-26-18-13-11-16-24(26)30(3,4)28(32)20-15-21-29-31(5,6)25-17-12-14-19-27(25)33(29)23-10-8-2,/h11-21H,7-10,22-23H2,1-6H3,1H/q+1,/p-1

DiIC4(3) is a fluorescent carbocyanine dye with butyl chains widely used for membrane staining due to its hydrophobic nature, which helps it intercalate well into lipid bilayers. Carbocyanine dyes are unique organic molecules that contain a conjugated electron-deficient system between two heterocyclic nitrogen atoms that provides characteristically long absorption and emission wavelengths. It can be used for cell tracking as it is stably retained in membranes and in fixed tissue slices for anterograde and retrograde tracing. Spectral Data: Excitation max: ~550-555nm, Emission max: ~565-570nm (accord. Lit). Also used as intermediate for the synthesis of selective protein arginine methyltransferases (PRMT) inhibitors. Intermediate for the synthesis of fluorescent probes.

Artikelnummer: D0224 Kategorie: Fluorescent Detection

Zusätzliche Informationen

Zusätzliche Informationen

Synonyms	DiIC4(3)
Purity	≥98% (HPLC)
Appearance	Violett crystalline solid
CAS-Number	132752-00-2
Molecular Formula	C31H41N2.I
Molecular Weight	568.58
Identity	1H-NMR
Solvents	DMSO or methanol
Melting Point	172-175 °C
Fluorescence	λex 506 nm; λem 578 nm in phosphate buffer/SDS pH 7.0
Smiles	CCCCN\1C2=CC=CC=C2C(/C1=C\C=C\C3=[N+](C4=CC=CC=C4C3(C)C)CCCC)(C)C.[I-]
InChi Key	CVTQMCMIKOZBTI-UHFFFAOYSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and air. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) G. Suaerwein & G.B. Schuster, J. Phys. Chem. 95, 1903 (1991), (2) G. Beckford, et al., Talanta 92, 45 (2012), (3) S.H. Sinha, et al., Eur. J. Med. Chem. 54, 647 (2012), (4) H. Hu, et al., J. Med. Chem. 58, 1228 (2015), (5) M. Matsui, et al., Tetrahedron 71, 3528 (2015)
InChi	InChI=1S/C31H41N2.HI/c1-7-9-22-32-26-18-13-11-16-24(26)30(3,4)28(32)20-15-21-29-31(5,6)25-17-12-14-19-27(25)33(29)23-10-8-2,/h11-21H,7-10,22-23H2,1-6H3,1H/q+1,/p-1
Quantity	50 mg, 100 mg, 250 mg, Bulk