Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white solid
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in acetonitrile, methanol or chloroform.
Available from stock
2-Methoxy-2,4-diphenyl-3(2H)-furanone
- SKU
- M0242
Category: Carbohydrates
- Synonyms
- MDPF, 2,4-Diphenyl-2-methoxy-3(2H)-furanone
- 50632-57-0
- CAS-Number
- C17H14O3
- Molecular Formula
- 266.29
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- 2-Methoxy-2,4-diphenyl-3(2H)-furanone (MDPF) is used as a sensitive fluorescent labeling reagent widely used to derivatize primary and secondary amines on molecules such as proteins. Upon derivatization, it produces highly stable and strongly fluorescent adducts, enabling reliable analysis by HPLC, fluorescence spectroscopy, or imaging techniques. MDPF is commonly applied in bioanalytical chemistry to measure amino acids, peptides, and amine-containing biomolecules, as well as in environmental and pharmaceutical studies for trace amine detection. Spectral Data: λEx=384 nm, λEm=472 nm (in acetonitrile after derivatization with hexylamine).
- Smiles
- O=C1C(C2=CC=CC=C2)=COC1(C3=CC=CC=C3)OC
- InChi Key
- BLWINLJDTOJSRU-UHFFFAOYSA-N
- References
- (1) S. Stein; Pept. Neurobiol. 9 (1977) , (2) M.A. Fishman, et al.; J. Neurochem. 32, 1077 (1979) , (3) R.L. O'Grady, et al.; Anal. Biochem. 140, 490 (1984) , (4) P. Jackson, et al.; Electrophoresis 9, 330 (1988) , (5) M. Hengstschlager, et al.; Cytometry 14, 39 (1993) , (6) J.C. Stockert & C.I. Trigoso; Blood Cells 19, 423 (1993) , (7) F.J. Alba, et al.; Electrophoresis 18, 1960 (1998) , (8) J.R. Daban; Electrophoresis 22, 874 (2001) , (9) K. Martin, et al.; Proteomics 3, 1215 (2003) , (10) D. Min, et al.; Electrophoresis 27, 357 (2006)
- InChi
- InChI=1S/C17H14O3/c1-19-17(14-10-6-3-7-11-14)16(18)15(12-20-17)13-8-4-2-5-9-13/h2-12H,1H3
2-Methoxy-2,4-diphenyl-3(2H)-furanone (MDPF) is used as a sensitive fluorescent labeling reagent widely used to derivatize primary and secondary amines on molecules such as proteins. Upon derivatization, it produces highly stable and strongly fluorescent adducts, enabling reliable analysis by HPLC, fluorescence spectroscopy, or imaging techniques. MDPF is commonly applied in bioanalytical chemistry to measure amino acids, peptides, and amine-containing biomolecules, as well as in environmental and pharmaceutical studies for trace amine detection. Spectral Data: λEx=384 nm, λEm=472 nm (in acetonitrile after derivatization with hexylamine).
Additional information
| Synonyms | MDPF, 2,4-Diphenyl-2-methoxy-3(2H)-furanone |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white solid |
| CAS-Number | 50632-57-0 |
| Molecular Formula | C17H14O3 |
| Molecular Weight | 266.29 |
| Identity | 1H-NMR |
| Solvents | Soluble in acetonitrile, methanol or chloroform. |
| Smiles | O=C1C(C2=CC=CC=C2)=COC1(C3=CC=CC=C3)OC |
| InChi Key | BLWINLJDTOJSRU-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) S. Stein; Pept. Neurobiol. 9 (1977), (2) M.A. Fishman, et al.; J. Neurochem. 32, 1077 (1979), (3) R.L. O'Grady, et al.; Anal. Biochem. 140, 490 (1984), (4) P. Jackson, et al.; Electrophoresis 9, 330 (1988), (5) M. Hengstschlager, et al.; Cytometry 14, 39 (1993), (6) J.C. Stockert & C.I. Trigoso; Blood Cells 19, 423 (1993), (7) F.J. Alba, et al.; Electrophoresis 18, 1960 (1998), (8) J.R. Daban; Electrophoresis 22, 874 (2001), (9) K. Martin, et al.; Proteomics 3, 1215 (2003), (10) D. Min, et al.; Electrophoresis 27, 357 (2006) |
| InChi | InChI=1S/C17H14O3/c1-19-17(14-10-6-3-7-11-14)16(18)15(12-20-17)13-8-4-2-5-9-13/h2-12H,1H3 |
| Quantity | 25 mg, 100 mg, Bulk |
