Available from stock

3,3′-Dipentyloxacarbocyanine iodide

SKU: D0128

Category: Fluorescent Detection

Synonyms: DiOC5(3), NK 2453; 53213-81-3
CAS-Number: C₂₇H₃₃IN₂O₂
Molecular Formula: 544.47
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Coral powder
Identity: 1H-NMR

Properties

Solvents: DMSO or DMF

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and air. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315, H319, H335
Precautionary statements: P264,P280,P302+P352,P321, P332+P313, P362, P280, P305+P351+P338, P337+P313, P201, P202,P281,P308+P313,P405,P501,P261,P271,P304+P340,P312,P403+P233
GHS Symbol: GHS07+GHS08
Signal word: Danger
Transportation: Not dangerous goods

Description: 3,3'-Dipentyloxacarbocyanine iodide is a lipophilic carbocyanine dye used primarily for membrane potential studies and cell labeling. Used to monitor mitochondrial or plasma membrane potential in live cells. The dye accumulates in polarized membranes and fluorescence intensity correlates with membrane potential. The dye can label lipid membranes due to its hydrophobic side chains and us useful for flow cytometry or fluorescence microscopy. Spectral data: λex 484 nm, λem 509 nm in methanol. Intermediate for the synthesis of fluorescent probes.
Smiles: C(CCCC)N1C=2C(OC1=CC=CC3=[N+](CCCCC)C=4C(O3)=CC=CC4)=CC=CC2.[I-]
InChi Key: CDLMLYASVIQVPH-UHFFFAOYSA-M
References: (1) G. Meissner, J. Biol. Chem. 256, 636 (1981) , (2) J.G. Monroe & J.C. Cambier, J. Immunol. 131, 2641 (1983) , (3) R.L. Gallo, et al., Arch. Biochem. Biophys. 235, 544 (1984) , (4) H.A. Crissman, et al., Exp. Cell Res. 174, 388 (1988) , (5) H.A. Crissman, et al., Methods Cell Biol. 33, 89 (1990) , (6) M. Yamashita, et al., FEBS J. 273, 3585 (2006) , (7) B. Zhang, et al., Biomaterials 52, 14 (2015)
InChi: InChI=1S/C27H33N2O2.HI/c1-3-5-11-20-28-22-14-7-9-16-24(22)30-26(28)18-13-19-27-29(21-12-6-4-2)23-15-8-10-17-25(23)31-27,/h7-10,13-19H,3-6,11-12,20-21H2,1-2H3,1H/q+1,/p-1

3,3′-Dipentyloxacarbocyanine iodide is a lipophilic carbocyanine dye used primarily for membrane potential studies and cell labeling. Used to monitor mitochondrial or plasma membrane potential in live cells. The dye accumulates in polarized membranes and fluorescence intensity correlates with membrane potential. The dye can label lipid membranes due to its hydrophobic side chains and us useful for flow cytometry or fluorescence microscopy. Spectral data: λex 484 nm, λem 509 nm in methanol. Intermediate for the synthesis of fluorescent probes.

SKU: D0128 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	DiOC5(3), NK 2453
Purity	≥98% (HPLC)
Appearance	Coral powder
CAS-Number	53213-81-3
Molecular Formula	C27H33IN2O2
Molecular Weight	544.47
Identity	1H-NMR
Solvents	DMSO or DMF
Smiles	C(CCCC)N1C=2C(OC1=CC=CC3=[N+](CCCCC)C=4C(O3)=CC=CC4)=CC=CC2.[I-]
InChi Key	CDLMLYASVIQVPH-UHFFFAOYSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and air. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315, H319, H335
Precautionary statements	P264,P280,P302+P352,P321, P332+P313, P362, P280, P305+P351+P338, P337+P313, P201, P202,P281,P308+P313,P405,P501,P261,P271,P304+P340,P312,P403+P233
GHS Symbol	GHS07+GHS08
Signal word	Danger
Transportation	Not dangerous goods
References	(1) G. Meissner, J. Biol. Chem. 256, 636 (1981), (2) J.G. Monroe & J.C. Cambier, J. Immunol. 131, 2641 (1983), (3) R.L. Gallo, et al., Arch. Biochem. Biophys. 235, 544 (1984), (4) H.A. Crissman, et al., Exp. Cell Res. 174, 388 (1988), (5) H.A. Crissman, et al., Methods Cell Biol. 33, 89 (1990), (6) M. Yamashita, et al., FEBS J. 273, 3585 (2006), (7) B. Zhang, et al., Biomaterials 52, 14 (2015)
InChi	InChI=1S/C27H33N2O2.HI/c1-3-5-11-20-28-22-14-7-9-16-24(22)30-26(28)18-13-19-27-29(21-12-6-4-2)23-15-8-10-17-25(23)31-27,/h7-10,13-19H,3-6,11-12,20-21H2,1-2H3,1H/q+1,/p-1
Quantity	50 mg, 100 mg, 250 mg, Bulk