Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- White to off-white powder
Properties
- Optical Activity
- [α]/D -76.0±5.0°, c = 0.5 in H2O
- Solvents
- DMSO (50 mg/ml), DMF (50 mg/ml), ethanol (20 mg/ml)
Available from stock
4-O-Caffeoylquinic acid
- SKU
- C0702
Category: Phytochemicals
- Synonyms
- 4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid , Cryptochlorogenic acid
- 905-99-7
- CAS-Number
- C16H18O9
- Molecular Formula
- 354.31
- Molecular Weight
- Shipping
- AMBIENT
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- +4°C
- Short Term Storage
- RT
- Transportation
- Not dangerous goods
- Description
- Cryptochlorogenic acid (isomer of chlorogenic acid) is a phenolic acid found in various plant species, displaying diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro. Cryptochlorogenic acid has antibiotic/antibacterial activity inhibiting the growth of S. aureus. It is an antioxidant and free radical scavenger in a cell-free assay. Cryptochlorogenic acid is allergenic, inducing degranulation of RBL-2H3 mast cells in vitro and increasing plasma serotonin and β-hexosaminidase levels in guinea pigs in vivo. Can be used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
- References
- (1) H.A. Jung, et al., Food Chem. Toxicol. 49, 376 (2011) , (2) J. Wang, et al., Molecules 19, 21226 (2014) , (3) H. Xu, et al., Food Sci. Biotech. 23, 2013 (2014) , (4) F. Wang, et al., J. Ethnopharmacol. 170, 1 (2015) , (5) L. Liang, et al., Comb. Chem. High Throughput Screen. 21, 292 (2018)
- InChi Key
- GYFFKZTYYAFCTR-PCNKEKKESA-N
- Smiles
- O[C@H]1[C@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)C[C@@](O)(C(O)=O)C1
Cryptochlorogenic acid (isomer of chlorogenic acid) is a phenolic acid found in various plant species, displaying diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro. Cryptochlorogenic acid has antibiotic/antibacterial activity inhibiting the growth of S. aureus. It is an antioxidant and free radical scavenger in a cell-free assay. Cryptochlorogenic acid is allergenic, inducing degranulation of RBL-2H3 mast cells in vitro and increasing plasma serotonin and β-hexosaminidase levels in guinea pigs in vivo. Can be used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
Zusätzliche Information
| Synonyms | 4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid, Cryptochlorogenic acid |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 905-99-7 |
| Molecular Formula | C16H18O9 |
| Molecular Weight | 354.31 |
| Identity | 1H-NMR |
| Solvents | DMSO (50 mg/ml), DMF (50 mg/ml), ethanol (20 mg/ml) |
| Optical Activity | [α]/D -76.0±5.0°, c = 0.5 in H2O |
| Smiles | O[C@H]1[C@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)C[C@@](O)(C(O)=O)C1 |
| InChi Key | GYFFKZTYYAFCTR-PCNKEKKESA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | (1) H.A. Jung, et al., Food Chem. Toxicol. 49, 376 (2011), (2) J. Wang, et al., Molecules 19, 21226 (2014), (3) H. Xu, et al., Food Sci. Biotech. 23, 2013 (2014), (4) F. Wang, et al., J. Ethnopharmacol. 170, 1 (2015), (5) L. Liang, et al., Comb. Chem. High Throughput Screen. 21, 292 (2018) |
| Quantity | 10 mg, 50 mg, Bulk |
