Available from stock

4-O-Caffeoylquinic acid

SKU: C0702

Category: Phytochemicals

Synonyms: 4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid , Cryptochlorogenic acid; 905-99-7
CAS-Number: C₁₆H₁₈O₉
Molecular Formula: 354.31
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: White to off-white powder
Identity: 1H-NMR

Properties

Solvents: DMSO (50 mg/ml), DMF (50 mg/ml), ethanol (20 mg/ml)
Optical Activity: [α]/D -76.0±5.0°, c = 0.5 in H2O

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: Cryptochlorogenic acid (isomer of chlorogenic acid) is a phenolic acid found in various plant species, displaying diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro. Cryptochlorogenic acid has antibiotic/antibacterial activity inhibiting the growth of S. aureus. It is an antioxidant and free radical scavenger in a cell-free assay. Cryptochlorogenic acid is allergenic, inducing degranulation of RBL-2H3 mast cells in vitro and increasing plasma serotonin and β-hexosaminidase levels in guinea pigs in vivo. Can be used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
Smiles: O[C@H]1[C@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)C[C@@](O)(C(O)=O)C1
InChi Key: GYFFKZTYYAFCTR-PCNKEKKESA-N
References: (1) H.A. Jung, et al., Food Chem. Toxicol. 49, 376 (2011) , (2) J. Wang, et al., Molecules 19, 21226 (2014) , (3) H. Xu, et al., Food Sci. Biotech. 23, 2013 (2014) , (4) F. Wang, et al., J. Ethnopharmacol. 170, 1 (2015) , (5) L. Liang, et al., Comb. Chem. High Throughput Screen. 21, 292 (2018)

Cryptochlorogenic acid (isomer of chlorogenic acid) is a phenolic acid found in various plant species, displaying diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro. Cryptochlorogenic acid has antibiotic/antibacterial activity inhibiting the growth of S. aureus. It is an antioxidant and free radical scavenger in a cell-free assay. Cryptochlorogenic acid is allergenic, inducing degranulation of RBL-2H3 mast cells in vitro and increasing plasma serotonin and β-hexosaminidase levels in guinea pigs in vivo. Can be used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).

Artikelnummer: C0702 Kategorie: Phytochemicals

Zusätzliche Informationen

Zusätzliche Informationen

Synonyms	4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid, Cryptochlorogenic acid
Purity	≥98% (HPLC)
Appearance	White to off-white powder
CAS-Number	905-99-7
Molecular Formula	C16H18O9
Molecular Weight	354.31
Identity	1H-NMR
Solvents	DMSO (50 mg/ml), DMF (50 mg/ml), ethanol (20 mg/ml)
Optical Activity	[α]/D -76.0±5.0°, c = 0.5 in H2O
Smiles	O[C@H]1[C@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)C[C@@](O)(C(O)=O)C1
InChi Key	GYFFKZTYYAFCTR-PCNKEKKESA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) H.A. Jung, et al., Food Chem. Toxicol. 49, 376 (2011), (2) J. Wang, et al., Molecules 19, 21226 (2014), (3) H. Xu, et al., Food Sci. Biotech. 23, 2013 (2014), (4) F. Wang, et al., J. Ethnopharmacol. 170, 1 (2015), (5) L. Liang, et al., Comb. Chem. High Throughput Screen. 21, 292 (2018)
Quantity	10 mg, 50 mg, Bulk