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    Balofloxacin

    Available from stock

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      Balofloxacin

      SKU
      B0302

      Category: Antibiotics

      Synonyms
      (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)piperidino]-4-oxo-3-quinolinecarboxylic acid
      127294-70-6
      CAS-Number
      C20H24FN3O4
      Molecular Formula
      389.42
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Identity
      UV/Vis
      Appearance
      White powder

      Properties

      Melting Point
      181-187 °C
      Solvents
      DMSO (10mg/ml)

      Downloads

      Safety Data Sheet
      CDX B0302 MSDS.pdf
      Shipping
      AMBIENT
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Handling Advice
      Protect from light and moisture.
      Long Term Storage
      +4°C
      Short Term Storage
      +4°C
      Transportation
      Not dangerous goods
      Description
      Fluoroquinolone antibiotic with potent bactericidal activity. Inhibits the synthesis of bacterial DNA by interfering with the the supercoiling activity of DNA gyrase.
      References
      (1) T. Ito, et al. , Antimicrob. Agents Chemother. 36, 1708 (1992) , (2) I. Takashima, et al. , Antimicrob. Agents Chemother. 37, 901 (1993) , (3) Y. Gohara, et al. , Antimicrob. Agents Chemother. 37, 1826 (1993) , (4) T. Ito, et al. , Biol. Pharm. Bull. 17, 927 (1994) , (5) N. Cho, et al. , Drugs 49, 391 (1995) , (6) H. Iwasaki, et al. , Chemotherapy 41, 100 (1995) , (7) T. Ito, et al. , Antimicrob. Agents Chemother. 39, 1522 (1995) , (8) L. Alksne , Curr. Opin. Investig. Drugs 4, 224 (2003) , (9) H. Jiang, et al. , J. Ocul. Pharmacol. Ther. 30, 482 (2014)
      InChi Key
      MGQLHRYJBWGORO-UHFFFAOYSA-N
      Smiles
      CNC(CCC1)CN1C2=C(F)C=C3C(N(C4CC4)C=C(C(O)=O)C3=O)=C2OC

      Fluoroquinolone antibiotic with potent bactericidal activity. Inhibits the synthesis of bacterial DNA by interfering with the the supercoiling activity of DNA gyrase.

      Artikelnummer: B0302 Kategorie: Antibiotics
      • Zusätzliche Information

      Zusätzliche Information

      Synonyms

      (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)piperidino]-4-oxo-3-quinolinecarboxylic acid

      Purity

      ≥98% (HPLC)

      Appearance

      White powder

      CAS-Number

      127294-70-6

      Molecular Formula

      C20H24FN3O4

      Molecular Weight

      389.42

      Identity

      UV/Vis

      Solvents

      DMSO (10mg/ml)

      Melting Point

      181-187 °C

      Smiles

      CNC(CCC1)CN1C2=C(F)C=C3C(N(C4CC4)C=C(C(O)=O)C3=O)=C2OC

      InChi Key

      MGQLHRYJBWGORO-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Transportation

      Not dangerous goods

      References

      (1) T. Ito, et al., Antimicrob. Agents Chemother. 36, 1708 (1992), (2) I. Takashima, et al., Antimicrob. Agents Chemother. 37, 901 (1993), (3) Y. Gohara, et al., Antimicrob. Agents Chemother. 37, 1826 (1993), (4) T. Ito, et al., Biol. Pharm. Bull. 17, 927 (1994), (5) N. Cho, et al., Drugs 49, 391 (1995), (6) H. Iwasaki, et al., Chemotherapy 41, 100 (1995), (7) T. Ito, et al., Antimicrob. Agents Chemother. 39, 1522 (1995), (8) L. Alksne, Curr. Opin. Investig. Drugs 4, 224 (2003), (9) H. Jiang, et al., J. Ocul. Pharmacol. Ther. 30, 482 (2014)

      Quantity

      25 mg, 100 mg, Bulk

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