beta-Cyclodextrin

Available from stock

beta-Cyclodextrin

SKU
C0261

Category:

Synonyms
β-Cyclodextrin , Caraway , Cycloheptaamylose , Cyclomaltoheptaose , Schardinger β-Dextrin
7585-39-9
CAS-Number
C42H70O35
Molecular Formula
1134.98
Molecular Weight

Specifications

Purity
≥98% (dry basis)
Identity
1H-NMR
Appearance
White crystalline powder

Properties

Density
1.44 g/cm3 at 20 °C
Optical Activity
[α]20/D +162±3°, c = 1.5% in H2O
Melting Point
290-300 °C (lit.)
Solvents
1 M NH4OH (50 mg/ml), water

Downloads

Safety Data Sheet
CDX C0261 MSDS.pdf
Shipping
AMBIENT
Use / Stability
Stable for at least 2 years after receipt when stored at RT.
Handling Advice
Protect from light and moisture.
Long Term Storage
RT
Short Term Storage
RT
Transportation
Not dangerous goods
Description
Most commonly used as a complexing agent in food, pharmaceutical, drug delivery and chemical industries, as well as agriculture and environmental engineering.. Forms complexes with hydrophobic compounds to enhance solubility and bioavailability (Drug Delivery System DDS). Commonly used to produce HPLC columns allowing chiral enantiomers separation. Used to remove large hydrophobic molecules like cholesterol. Reported to be useful for the selective precipitation of enantiomeric, positional or structural isomers. Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units with hydrophobic interiors, usually referred to as alpha-, beta- or gamma-cyclodextrins, respectively. Lipophilic drugs of a size compatible with the hydrophobic core of a cyclodextrin can form complexes, resulting in increased aqueous solubility of the drugs. Cyclodextrins are non-toxic in many species and do not denature proteins or interfere with enzymatic reactions.
InChi
InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1
References
E.M. Martin Del Valle, Process Biochem. 39, 1033 (2004) (Review) , G. Crini, Chem. Rev. 114, 10940 (2014) (Review)
InChi Key
WHGYBXFWUBPSRW-FOUAGVGXSA-N
Smiles
C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O

Most commonly used as a complexing agent in food, pharmaceutical, drug delivery and chemical industries, as well as agriculture and environmental engineering.. Forms complexes with hydrophobic compounds to enhance solubility and bioavailability (Drug Delivery System DDS). Commonly used to produce HPLC columns allowing chiral enantiomers separation. Used to remove large hydrophobic molecules like cholesterol. Reported to be useful for the selective precipitation of enantiomeric, positional or structural isomers. Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units with hydrophobic interiors, usually referred to as alpha-, beta- or gamma-cyclodextrins, respectively. Lipophilic drugs of a size compatible with the hydrophobic core of a cyclodextrin can form complexes, resulting in increased aqueous solubility of the drugs. Cyclodextrins are non-toxic in many species and do not denature proteins or interfere with enzymatic reactions.

Artikelnummer: C0261 Kategorie:

Zusätzliche Information

Synonyms

β-Cyclodextrin, Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardinger β-Dextrin
Purity

≥98% (dry basis)
Appearance

White crystalline powder
CAS-Number

7585-39-9
Molecular Formula

C42H70O35
Molecular Weight

1134.98
Identity

1H-NMR
Solvents

1 M NH4OH (50 mg/ml), water
Melting Point

290-300 °C (lit.)
Optical Activity

[α]20/D +162±3°, c = 1.5% in H2O
Density

1.44 g/cm3 at 20 °C
Smiles

C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O
InChi Key

WHGYBXFWUBPSRW-FOUAGVGXSA-N
Shipping

AMBIENT
Short Term Storage

RT
Long Term Storage

RT
Handling Advice

Protect from light and moisture.
Use / Stability

Stable for at least 2 years after receipt when stored at RT.
Transportation

Not dangerous goods
References

E.M. Martin Del Valle, Process Biochem. 39, 1033 (2004) (Review), G. Crini, Chem. Rev. 114, 10940 (2014) (Review)
InChi

InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1
Quantity

25 g, 100 g, 500 g, Bulk

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