Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- water
Category: Vitamins
NAD+, known more formally as nicotinamide adenine dinucleotide, is a signaling molecule as well as a cofactor or substrate for many enzymes. It acts as an oxidizing agent, accepting electrons from other molecules while being converted to its reduced form, NADH. NAD+ is also essential for the activity of several enzymes, including poly(ADP)-ribose polymerases and cADP-ribose synthases. For example, it is used by some sirtuins to mediate protein deacetylation, producing O-acetyl-ADP-ribose and nicotinamide as well as the deacetylated protein. NAD+ is an important player and factor to research metabolic pathways and pathologies.
Synonyms | beta-DPN, beta-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide, NSC 20272 |
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Purity | ≥98% (HPLC) |
Appearance | White to yellow powder |
CAS-Number | 53-84-9 |
Molecular Formula | C21H27N7O14P2 · xH2O |
Molecular Weight | 663.43 (anhydrous basis) |
Identity | 1H-NMR |
Solvents | water |
Smiles | O[C@H]1C(N2C=NC3=C2N=CN=C3N)O[C@H](COP(O)(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@@H]([N+]5=CC(C(N)=O)=CC=C5)O4)([O-])=O)=O)[C@H]1O |
InChi Key | BAWFJGJZGIEFAR-OMYDKTABSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | (1) B. Schwer & E. Verdin, Cell Metabolism 7, 104 (2008) (Review), (2) R.H. Houtkooper, et al., Endocr. Rev. 31, 194 (2010) (Review), (3) Y.S. Elhassan, et al., J. Endocr. Soc. 1, 816 (2017) (Review) |
InChi | InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20+,21?/m1/s1 |
Quantity | 1 g, 5 g, 10 g, Bulk |