Specifications
- Purity
- ≥97%
- Identity
- 1H-NMR
- Appearance
- White to off-white powder
Properties
- Solvents
- ethanol, chloroform, DMSO, water (insoluble)
Downloads
- Safety Data Sheet
- CDX C0694 MSDS.pdf
Available from stock
Cinchocaine
- SKU
- C0694
Category: API's & Intermediates
- Synonyms
- Dibucaine , NSC 159055 , 2-Butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide
- 85-79-0
- CAS-Number
- C20H29N3O2
- Molecular Formula
- 343.46
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Long Term Storage
- -20°C
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P280-P305+P351+P338-P310
- Hazard statements
- H302-H315-H319-H332-H335
- Description
- Cinchocaine is an amide local anesthetic. It is among the most potent and toxic of the long-acting local anesthetics, by blocking sodium channels. Shown to be a calpain activator inducing platelet apoptosis and to induce apoptosis in leukemia cells. This compound can be used as a reference compound.
- References
- (1) A. Fisher & R. Bryce-Smith, Anaesthesia 26, 324 (1971) , (2) K. Arita, et al., Biochem. Pharmacol. 60, 905 (2000) , (3) H.A. Douglas, et al., J. Neurophysiol. 105, 1482 (2011) , (4) W. Zhang, et al., Int. J. Mol. Sci. 12, 2125 (2011) , (5) K. Tonooka, et al., Forensic Sci. Int. 265, 182 (2016)
- InChi Key
- PUFQVTATUTYEAL-UHFFFAOYSA-N
- Smiles
- O=C(NCCN(CC)CC)C1=CC(OCCCC)=NC2=CC=CC=C21
Cinchocaine is an amide local anesthetic. It is among the most potent and toxic of the long-acting local anesthetics, by blocking sodium channels. Shown to be a calpain activator inducing platelet apoptosis and to induce apoptosis in leukemia cells. This compound can be used as a reference compound.
Zusätzliche Information
| Synonyms | Dibucaine, NSC 159055, 2-Butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide |
|---|---|
| Purity | ≥97% |
| Appearance | White to off-white powder |
| CAS-Number | 85-79-0 |
| Molecular Formula | C20H29N3O2 |
| Molecular Weight | 343.46 |
| Identity | 1H-NMR |
| Solvents | ethanol, chloroform, DMSO, water (insoluble) |
| Smiles | O=C(NCCN(CC)CC)C1=CC(OCCCC)=NC2=CC=CC=C21 |
| InChi Key | PUFQVTATUTYEAL-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) A. Fisher & R. Bryce-Smith, Anaesthesia 26, 324 (1971), (2) K. Arita, et al., Biochem. Pharmacol. 60, 905 (2000), (3) H.A. Douglas, et al., J. Neurophysiol. 105, 1482 (2011), (4) W. Zhang, et al., Int. J. Mol. Sci. 12, 2125 (2011), (5) K. Tonooka, et al., Forensic Sci. Int. 265, 182 (2016) |
| Quantity | 5 g, 10 g, Bulk |
