D-Mannitol

Available from stock

D-Mannitol

SKU
M0228

Category:

Synonyms
Mannite , Osmitrol , Cordycepic acid
69-65-8
CAS-Number
C6H14O6
Molecular Formula
182.17
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Specifications

Purity
≥97% (HPLC)
Appearance
White crystalline powder
Identity
1H-NMR

Properties

Solvents
water
Melting Point
166.2-167.3 °C
Boiling Point
290-295 °C
Shipping
AMBIENT
Short Term Storage
RT
Long Term Storage
RT
Handling Advice
Protect from light and moisture.
Use / Stability
Stable for at least 2 years after receipt when stored at RT.
Transportation
Not dangerous goods
Description
Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.
Smiles
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
InChi Key
FBPFZTCFMRRESA-KVTDHHQDSA-N
References
Q. Wang, et al., Drug Metab. Dispos. 36, 2244 (2008) , M. Turina, et al., Inflammation 31, 74 (2008) , A. Nishiyama, et al., J. Nutr. Sci. Vitaminol. 55, 242 (2009) , B.C. Saha & F.M. Racine, Appl. Microbiol. Biotechnol. 89, 879 (2011) , A. Kumar, et al., J. Clin. Diagn. Res. 8, GE01 (2014) , H.L. Ohrem, et al., Pharm. Dev. Technol. 19, 257 (2014) , P. André & F. Villain, Int. J. Cosmet. Sci. (2016)
InChi
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.

Artikelnummer: M0228 Kategorie:

Zusätzliche Informationen

Synonyms

Mannite, Osmitrol, Cordycepic acid
Purity

≥97% (HPLC)
Appearance

White crystalline powder
CAS-Number

69-65-8
Molecular Formula

C6H14O6
Molecular Weight

182.17
Identity

1H-NMR
Solvents

water
Melting Point

166.2-167.3 °C
Boiling Point

290-295 °C
Smiles

OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
InChi Key

FBPFZTCFMRRESA-KVTDHHQDSA-N
Shipping

AMBIENT
Short Term Storage

RT
Long Term Storage

RT
Handling Advice

Protect from light and moisture.
Use / Stability

Stable for at least 2 years after receipt when stored at RT.
Transportation

Not dangerous goods
References

Q. Wang, et al., Drug Metab. Dispos. 36, 2244 (2008), M. Turina, et al., Inflammation 31, 74 (2008), A. Nishiyama, et al., J. Nutr. Sci. Vitaminol. 55, 242 (2009), B.C. Saha & F.M. Racine, Appl. Microbiol. Biotechnol. 89, 879 (2011), A. Kumar, et al., J. Clin. Diagn. Res. 8, GE01 (2014), H.L. Ohrem, et al., Pharm. Dev. Technol. 19, 257 (2014), P. André & F. Villain, Int. J. Cosmet. Sci. (2016)
InChi

InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
Quantity

500 g, Bulk

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