Specifications
- Purity
- ≥98% (TLC)
- Appearance
- Yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (10mg/ml), DMF (20mg/ml), methanol, ethanol (5mg/ml)
Available from stock
Luteolin
- SKU
- L0087
Category: Lipids, Fatty Acids
- Synonyms
- 3',4',5,7-Tetrahydroxyflavone , Luteolol , BRN 0292084 , C.I. Natural Yellow 2 , Digitoflavone , Flacitran , Flavopurpol , Daphneflavonol , Argemexitin
- 491-70-3
- CAS-Number
- C15H10O6
- Molecular Formula
- 286.24
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Transportation
- Not dangerous goods
- Description
- Luteolin is a hydroxylated flavone derivative that is a strong antioxidant and radical scavenger. It has multiple activities, such as anticancer, antimetastatic, anti-adipogenic, anti-inflammatory and neuroprotective. Luteolin has been described as a fatty acid synthase (FASN), 15-lipoxygenase, alpha-glucosidase, PPAR-γ, topoisomerase I, PI3K/Akt, RSK1/RSK2 and HDAC inhibitor.
- Smiles
- OC1=C2C(OC(C3=CC(O)=C(O)C=C3)=CC2=O)=CC(O)=C1
- InChi Key
- IQPNAANSBPBGFQ-UHFFFAOYSA-N
- References
- (1) Y.T. Huang, et al., Br. J. Pharmacol. 128, 999 (1999) , (2) J.S. Kim, et al., Biosci. Biotechnol. Biochem. 64, 2458 (2000) , (3) H. Ueda, et al., Biol. Pharm. Bull. 25, 1197 (2002) , (4) A.R. Chowdhury, et al., Biochem. J. 366, 653 (2002) , (5) L. Sartor, et al., Biochem. Pharmacol. 64, 229 (2002) , (6) C.D. Sadik, et al., Biochem. Pharmacol. 65, 773 (2003) , (7) D.T. Coleman, et al., Mol. Cancer Ther. 8, 214 (2009) , (8) K. Xu, et al., Molecules 14, 3486 (2009) , (9) H.S. Park, et al., Biofactors 35, 373 (2009) , (10) S. Attoub, et al., Eur. J. Pharmacol. 651, 18 (2011) , (11) H.Y. Kim, et al., Phytother. Res. 27, 1481 (2013) , (12) K.M. Reipas, et al., Oncotarget 4, 329 (2013)
Luteolin is a hydroxylated flavone derivative that is a strong antioxidant and radical scavenger. It has multiple activities, such as anticancer, antimetastatic, anti-adipogenic, anti-inflammatory and neuroprotective. Luteolin has been described as a fatty acid synthase (FASN), 15-lipoxygenase, alpha-glucosidase, PPAR-γ, topoisomerase I, PI3K/Akt, RSK1/RSK2 and HDAC inhibitor.
Zusätzliche Informationen
| Synonyms | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol, Daphneflavonol, Argemexitin |
|---|---|
| Purity | ≥98% (TLC) |
| Appearance | Yellow powder |
| CAS-Number | 491-70-3 |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.24 |
| Identity | 1H-NMR |
| Solvents | DMSO (10mg/ml), DMF (20mg/ml), methanol, ethanol (5mg/ml) |
| Smiles | OC1=C2C(OC(C3=CC(O)=C(O)C=C3)=CC2=O)=CC(O)=C1 |
| InChi Key | IQPNAANSBPBGFQ-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | (1) Y.T. Huang, et al., Br. J. Pharmacol. 128, 999 (1999), (2) J.S. Kim, et al., Biosci. Biotechnol. Biochem. 64, 2458 (2000), (3) H. Ueda, et al., Biol. Pharm. Bull. 25, 1197 (2002), (4) A.R. Chowdhury, et al., Biochem. J. 366, 653 (2002), (5) L. Sartor, et al., Biochem. Pharmacol. 64, 229 (2002), (6) C.D. Sadik, et al., Biochem. Pharmacol. 65, 773 (2003), (7) D.T. Coleman, et al., Mol. Cancer Ther. 8, 214 (2009), (8) K. Xu, et al., Molecules 14, 3486 (2009), (9) H.S. Park, et al., Biofactors 35, 373 (2009), (10) S. Attoub, et al., Eur. J. Pharmacol. 651, 18 (2011), (11) H.Y. Kim, et al., Phytother. Res. 27, 1481 (2013), (12) K.M. Reipas, et al., Oncotarget 4, 329 (2013) |
| Quantity | 10 mg, 50 mg, Bulk |
