Available from stock

Methsuximide

SKU: M0153

Category: API's & Intermediates

Synonyms: Mesuximide , 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione , 1,3-Dimethyl-3-phenylsuccinimide , PM 396; 77-41-8
CAS-Number: C₁₂H₁₃NO₂
Molecular Formula: 203.24
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (GC)
Appearance: White powder
Identity: 1H-NMR

Properties

Solvents: chloroform, methanol, DMSO
Melting Point: 52 - 53 °C
Boiling Point: 346.4±31.0 °C at 760 mmHg
Refractive Index: 1.552

Documentation

Safety Data Sheet (SDS): CDX M0153 MSDS.pdf

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H302-H412
Precautionary statements: P301 + P312 + P330
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: A succinimide with anti-epileptic and anti-convulsant properties. The mechanisms of action are unknown and possibly multiple. Metabolically reduced to it's pharmacologically active metabolite N-desmethylmethosuximide.
Smiles: O=C(C(C1=CC=CC=C1)(C)C2)N(C)C2=O
InChi Key: AJXPJJZHWIXJCJ-UHFFFAOYSA-N
References: (1) C.A. Miller, et al.: JACS 73, 4895 (1951) , (2) C.A. Miller, et al.: JACS 73, 5608 (1951) , (3) G. Chen, et al.: Epilepsia 4, 66 (1963) , (4) J.M. Strong, et al.: Neurology 24, 250 (1974) , (5) T.R. Browne, et al.: Neurology 33, 414 (1983)
InChi: InChI=1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,1-2H3

A succinimide with anti-epileptic and anti-convulsant properties. The mechanisms of action are unknown and possibly multiple. Metabolically reduced to it’s pharmacologically active metabolite N-desmethylmethosuximide.

SKU: M0153 Category: API's & Intermediates

Additional information

Additional information

Synonyms	Mesuximide, 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione, 1,3-Dimethyl-3-phenylsuccinimide, PM 396
Purity	≥98% (GC)
Appearance	White powder
CAS-Number	77-41-8
Molecular Formula	C12H13NO2
Molecular Weight	203.24
Identity	1H-NMR
Solvents	chloroform, methanol, DMSO
Melting Point	52 – 53 °C
Boiling Point	346.4±31.0 °C at 760 mmHg
Refractive Index	1.552
Smiles	O=C(C(C1=CC=CC=C1)(C)C2)N(C)C2=O
InChi Key	AJXPJJZHWIXJCJ-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H302-H412
Precautionary statements	P301 + P312 + P330
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) C.A. Miller, et al.: JACS 73, 4895 (1951), (2) C.A. Miller, et al.: JACS 73, 5608 (1951), (3) G. Chen, et al.: Epilepsia 4, 66 (1963), (4) J.M. Strong, et al.: Neurology 24, 250 (1974), (5) T.R. Browne, et al.: Neurology 33, 414 (1983)
InChi	InChI=1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,1-2H3
Quantity	50 mg, 100 mg, Bulk