Specifications
- Purity
- ≥95% (TLC)
- Appearance
- Solid
- Identity
- 1H-NMR
Properties
- Solvents
- water, DMSO
Documentation
- Safety Data Sheet (SDS)
- CDX A0191 MSDS_V1.2.pdf
Available from stock
N-(2-Aminoethyl)biotinamide hydrochloride
- SKU
- A0191
Category: Non Fluorescent Detection & Chromogene Detection
- Synonyms
- Neurobiotin
- 111822-45-8
- CAS-Number
- C12H23ClN4O2S
- Molecular Formula
- 322.85
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Transportation
- Not dangerous goods
- Description
- Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
- Smiles
- Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2
- InChi Key
- UWYKXZBFDOWDHO-GRIHUTHFSA-N
- References
- (1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002) , (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997) , (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988)
- InChi
- InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11
Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
Zusätzliche Informationen
| Synonyms | Neurobiotin |
|---|---|
| Purity | ≥95% (TLC) |
| Appearance | Solid |
| CAS-Number | 111822-45-8 |
| Molecular Formula | C12H23ClN4O2S |
| Molecular Weight | 322.85 |
| Identity | 1H-NMR |
| Solvents | water, DMSO |
| Smiles | Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2 |
| InChi Key | UWYKXZBFDOWDHO-GRIHUTHFSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002), (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997), (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988) |
| InChi | InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11 |
| Quantity | 50 mg, 1 g, Bulk |
