Specifications
- Purity
- ≥97% (NMR)
- Identity
- 1H-NMR
- Appearance
- Yellow to orange powder
Properties
- Fluorescence
- λex 360 nm, λem 530 nm±10 nm in methanol
- Solvents
- Slightly methanol (1 mg/ml)
Available from stock
N-Dansylethylenediamine
- SKU
- C0068
Category: Fluorescent Detection
- Synonyms
- N-Dansylethylenediamine , N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide , N-(2-Aminoethyl)dansylamide , DNSEDA , NSC 666752 , Dansyl EDA
- 35060-08-3
- CAS-Number
- C14H19N3O2S
- Molecular Formula
- 293.38
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Long Term Storage
- -20°C
- Short Term Storage
- -20°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P261-P305+P351+P338
- Hazard statements
- H302-H315-H319-H335
- Description
- Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
- InChi
- InChI=1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3
- References
- (1) H. Adachi, et al., Biochim. Biophys. Acta 1163, 42 (1993) , (2) A. Sonoki, et al., J. Liqu. Chrom. Rel. Technol. 17, 1057 (1994) , (3) J. Moraczewska, et al., Biophys J. 77, 373 (1999) , (4) L. Prodi, et al., Hel. Chim. Acta 84, 690 (2001) , (5) S. Mallampati, et al., Electrophoresis 28, 3948 (2007) , (6) R.W. Dudley, et al., Mol. Cell Biochem. 346, 81 (2011) , (7) Y. Inoue, et al., Biosens. Bioelectron. 48, 113 (2013)
- InChi Key
- CSJXLKVNKAXFSI-UHFFFAOYSA-N
- Smiles
- CN(C)C1=C(C=CC=C2S(=O)(NCCN)=O)C2=CC=C1
Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
Zusätzliche Information
| Synonyms | N-Dansylethylenediamine, N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Aminoethyl)dansylamide, DNSEDA, NSC 666752, Dansyl EDA |
|---|---|
| Purity | ≥97% (NMR) |
| Appearance | Yellow to orange powder |
| CAS-Number | 35060-08-3 |
| Molecular Formula | C14H19N3O2S |
| Molecular Weight | 293.38 |
| Identity | 1H-NMR |
| Solvents | Slightly methanol (1 mg/ml) |
| Fluorescence | λex 360 nm, λem 530 nm±10 nm in methanol |
| Smiles | CN(C)C1=C(C=CC=C2S(=O)(NCCN)=O)C2=CC=C1 |
| InChi Key | CSJXLKVNKAXFSI-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) H. Adachi, et al., Biochim. Biophys. Acta 1163, 42 (1993), (2) A. Sonoki, et al., J. Liqu. Chrom. Rel. Technol. 17, 1057 (1994), (3) J. Moraczewska, et al., Biophys J. 77, 373 (1999), (4) L. Prodi, et al., Hel. Chim. Acta 84, 690 (2001), (5) S. Mallampati, et al., Electrophoresis 28, 3948 (2007), (6) R.W. Dudley, et al., Mol. Cell Biochem. 346, 81 (2011), (7) Y. Inoue, et al., Biosens. Bioelectron. 48, 113 (2013) |
| InChi | InChI=1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3 |
| Quantity | 500 mg, 1 g, Bulk |
