Specifications
- Purity
- ≥98% (TLC)
- Appearance
- White to faint yellow powder or crystals
- Identity
- 1H-NMR
Properties
- Solvents
- water (40 mg/ml), ethanol, DMSO
Available from stock
Pancuronium bromide
- SKU
- P0238
Category: Steroids
- Synonyms
- NSC 293162
- 15500-66-0
- CAS-Number
- C35H60Br2N2O4
- Molecular Formula
- 732.67
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H301
- Precautionary statements
- P301 + P310
- GHS Symbol
- GHS06
- Signal word
- Danger
- RIDADR
- UN2811
- Transportation
- Packing Group III
- Description
- Pancuronium bromide is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) acting as a typical non-depolarizing curare-mimetic muscle relaxant/neuromuscular blocking agent. Pancuronium bromide enhances anesthesia induced by isoflurane.
- Smiles
- O=C(C)O[C@H]1[C@@H]([N+]2(C)CCCCC2)C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H]([N+]6(C)CCCCC6)C[C@]5(C)[C@@]4([H])CC[C@@]31C.[Br-].[Br-]
- InChi Key
- NPIJXCQZLFKBMV-YTGGZNJNSA-L
- References
- (1) W.R. Buckett, et al., Br. J. Pharmacol. Chemother. 32, 671 (1968) , (2) D. Komesaroff & J.E. Field, Med. J. Aust. 1, 908 (1969) , (3) P.R. Saxena & I.L. Bonta, Arch. Int. Pharmacodyn. Ther. 189, 410 (1971) , (4) T.M. Speight & G.S. Avery, Drugs 4, 163 (1972) (Review) , (5) M. Liu & J.P. Dilger, Mol. Pharmacol. 75, 166 (2009) , (6) Y. Miyazaki, et al., J. Anesth. 30, 671 (2016)
- InChi
- InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36,,/h26-33H,7-23H2,1-6H3,2*1H/q+2,,/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-,,/m0../s1
Pancuronium bromide is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) acting as a typical non-depolarizing curare-mimetic muscle relaxant/neuromuscular blocking agent. Pancuronium bromide enhances anesthesia induced by isoflurane.
Additional information
| Synonyms | NSC 293162 |
|---|---|
| Purity | ≥98% (TLC) |
| Appearance | White to faint yellow powder or crystals |
| CAS-Number | 15500-66-0 |
| Molecular Formula | C35H60Br2N2O4 |
| Molecular Weight | 732.67 |
| Identity | 1H-NMR |
| Solvents | water (40 mg/ml), ethanol, DMSO |
| Smiles | O=C(C)O[C@H]1[C@@H]([N+]2(C)CCCCC2)C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H]([N+]6(C)CCCCC6)C[C@]5(C)[C@@]4([H])CC[C@@]31C.[Br-].[Br-] |
| InChi Key | NPIJXCQZLFKBMV-YTGGZNJNSA-L |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | UN2811 |
| Transportation | Packing Group III |
| References | (1) W.R. Buckett, et al., Br. J. Pharmacol. Chemother. 32, 671 (1968), (2) D. Komesaroff & J.E. Field, Med. J. Aust. 1, 908 (1969), (3) P.R. Saxena & I.L. Bonta, Arch. Int. Pharmacodyn. Ther. 189, 410 (1971), (4) T.M. Speight & G.S. Avery, Drugs 4, 163 (1972) (Review), (5) M. Liu & J.P. Dilger, Mol. Pharmacol. 75, 166 (2009), (6) Y. Miyazaki, et al., J. Anesth. 30, 671 (2016) |
| InChi | InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36,,/h26-33H,7-23H2,1-6H3,2*1H/q+2,,/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-,,/m0../s1 |
| Quantity | 10 mg, 50 mg, 100 mg, Bulk |
