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    Phenoxazine

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      Phenoxazine

      SKU
      P0144

      Category: Non Fluorescent Detection & Chromogene Detection

      Synonyms
      10H-Phenoxazine, 2,3,5,6-Dibenzo-1,4-oxazine, NSC72990
      135-67-1
      CAS-Number
      C12H9NO
      Molecular Formula
      183.2
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (NMR)
      Appearance
      White to faint grey powder
      Identity
      1H-NMR

      Properties

      Solvents
      ethanol (20mg/ml), DMSO (10mg/ml) or chloroform Inwater
      Melting Point
      156-159 °C (lit.)
      Shipping
      AMBIENT
      Short Term Storage
      RT
      Long Term Storage
      RT
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at RT.
      Transportation
      Not dangerous goods
      Description
      Phenoxazine is a heterocyclic building block. It has been used in the synthesis of phenoxazine derivatives that have anticancer and antimicrobial activities in vitro. Phenoxazine has also been used in the synthesis of phenoxazine derivatives used as fluorescent and chromogenic substrates.
      Smiles
      C1=2C(OC=3C(N1)=CC=CC3)=CC=CC2
      InChi Key
      TZMSYXZUNZXBOL-UHFFFAOYSA-N
      References
      (1) S. Shimizu, et al., Tohoku J. Exp. Med. 203, 47 (2004) , (2) X.-F. Che, et al., Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 87, 199 (2011) , (3) S. Shukla, et al., Synth. Commun. 48, 1377 (2018) , (4) N.C. Jana, et al., Polyhedron 164, 23 (2019) , (5) S. Shukla, et al., Mini Rev. Med. Chem. 21, 1541 (2021) (Review) , (6) M.V. Pavliuk, et al., Chem. Commun. 59, 5611 (2023) , (7) H. Al-Sharji, et al., Top. Curr. Chem. 382, 5 (2024) (Review) , (8) C. Sadhu & A.K. Mitra, Mol. Divers. 28, 965 (2024)
      InChi
      InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H

      Phenoxazine is a heterocyclic building block. It has been used in the synthesis of phenoxazine derivatives that have anticancer and antimicrobial activities in vitro. Phenoxazine has also been used in the synthesis of phenoxazine derivatives used as fluorescent and chromogenic substrates.

      SKU: P0144 Category: Non Fluorescent Detection & Chromogene Detection
      • Additional information

      Additional information

      Synonyms

      10H-Phenoxazine, 2,3,5,6-Dibenzo-1,4-oxazine, NSC72990

      Purity

      ≥98% (NMR)

      Appearance

      White to faint grey powder

      CAS-Number

      135-67-1

      Molecular Formula

      C12H9NO

      Molecular Weight

      183.2

      Identity

      1H-NMR

      Solvents

      ethanol (20mg/ml), DMSO (10mg/ml) or chloroform Inwater

      Melting Point

      156-159 °C (lit.)

      Smiles

      C1=2C(OC=3C(N1)=CC=CC3)=CC=CC2

      InChi Key

      TZMSYXZUNZXBOL-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      RT

      Long Term Storage

      RT

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at RT.

      Transportation

      Not dangerous goods

      References

      (1) S. Shimizu, et al., Tohoku J. Exp. Med. 203, 47 (2004), (2) X.-F. Che, et al., Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 87, 199 (2011), (3) S. Shukla, et al., Synth. Commun. 48, 1377 (2018), (4) N.C. Jana, et al., Polyhedron 164, 23 (2019), (5) S. Shukla, et al., Mini Rev. Med. Chem. 21, 1541 (2021) (Review), (6) M.V. Pavliuk, et al., Chem. Commun. 59, 5611 (2023), (7) H. Al-Sharji, et al., Top. Curr. Chem. 382, 5 (2024) (Review), (8) C. Sadhu & A.K. Mitra, Mol. Divers. 28, 965 (2024)

      InChi

      InChI=1S/C12H9NO/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H

      Quantity

      1 g, 5 g, Bulk

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