Tris(hydroxymethyl)aminomethane

Available from stock

Tris(hydroxymethyl)aminomethane

SKU
T0244

Category:

Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediol , THAM , Tris base , Trometamol
77-86-1
CAS-Number
C4H11NO3
Molecular Formula
121.14
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Specifications

Purity
≥99%
Appearance
White to off-white powder
Identity
1H-NMR

Properties

Solvents
water (550 mg/ml), methanol (26 mg/ml), anhydrous ethanol (14.6 mg/ml), DMF (14 mg/ml), acetone (2 mg/ml)
Melting Point
168-172 °C

Documentation

Safety Data Sheet (SDS)
CDX T0244 MSDS.pdf
Shipping
AMBIENT
Short Term Storage
RT
Long Term Storage
RT
Handling Advice
Protect from light and moisture.
Use / Stability
Stable for at least 2 years after receipt when stored at RT.
Transportation
Not dangerous goods
Description
A high quality buffer used in the range of physiological pH 7-9. Widely used as a biological buffer or as a component of buffer formulations. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
Smiles
NC(CO)(CO)CO
InChi Key
LENZDBCJOHFCAS-UHFFFAOYSA-N
References
(1) R.H. Kallet, et al. , Am. J. Respir. Crit. Care Med. 161, 1149 (2000) , (2) W.T. Desmarais, et al. , Structure 10, 1063 (2002) , (3) Z. Ghalanbor, et al. , Protein Pept. Lett. 15, 212 (2008) , (4) J. Sambrook, & D.W. Russell , Molecular Cloning: A Laboratory Manual (2012)

A high quality buffer used in the range of physiological pH 7-9. Widely used as a biological buffer or as a component of buffer formulations. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.

SKU: T0244 Category:

Additional information

Synonyms

2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
Purity

≥99%
Appearance

White to off-white powder
CAS-Number

77-86-1
Molecular Formula

C4H11NO3
Molecular Weight

121.14
Identity

1H-NMR
Solvents

water (550 mg/ml), methanol (26 mg/ml), anhydrous ethanol (14.6 mg/ml), DMF (14 mg/ml), acetone (2 mg/ml)
Melting Point

168-172 °C
Smiles

NC(CO)(CO)CO
InChi Key

LENZDBCJOHFCAS-UHFFFAOYSA-N
Shipping

AMBIENT
Short Term Storage

RT
Long Term Storage

RT
Handling Advice

Protect from light and moisture.
Use / Stability

Stable for at least 2 years after receipt when stored at RT.
Transportation

Not dangerous goods
References

(1) R.H. Kallet, et al., Am. J. Respir. Crit. Care Med. 161, 1149 (2000), (2) W.T. Desmarais, et al., Structure 10, 1063 (2002), (3) Z. Ghalanbor, et al., Protein Pept. Lett. 15, 212 (2008), (4) J. Sambrook, & D.W. Russell, Molecular Cloning: A Laboratory Manual (2012)
Quantity

500 g, Bulk

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