Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- ethyl acetate
Documentation
- Safety Data Sheet (SDS)
- CDX C0312 MSDS.pdf
Available from stock
1-(4′-Carboxybutyl)-3,7-dimethylxanthine
- SKU
- C0312
Category: Metabolites
- Synonyms
- 2,3,6,7-Tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purine-1-pentanoic acid DB-dmx
- 38975-44-9
- CAS-Number
- C12H16N4O4
- Molecular Formula
- 280.28
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H302
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-? cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the ?-2 integrin CD11b/CD18.
- Smiles
- CN(C1=C2N(C)C=N1)C(N(CCCCC(O)=O)C2=O)=O
- InChi Key
- JDMFPLGXRUJOTC-UHFFFAOYSA-N
- References
- (1) S. Hayashi, et al.: Chem. Pharm. Bull. 24, 1384 (1976) , (2) T.A. Bryce, et al.: J. Chromatogr. 344, 397 (1985) , (3) G.W. Sullivan, et al.: Infect. Immun. 56, 1722 (1988) , (4) M. Fantin, et al.: Eur. J. Pharmacol. 301, 535 (2006) , (5) M. Magnusson, et al.: Eur. J. Pharmacol. 290, 581 (2008)
- InChi
- InChI=1S/C12H16N4O4/c1-14-7-13-10-9(14)11(19)16(12(20)15(10)2)6-4-3-5-8(17)18/h7H,3-6H2,1-2H3,(H,17,18)
Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-? cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the ?-2 integrin CD11b/CD18.
Additional information
| Synonyms | 2,3,6,7-Tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purine-1-pentanoic acid DB-dmx |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White powder |
| CAS-Number | 38975-44-9 |
| Molecular Formula | C12H16N4O4 |
| Molecular Weight | 280.28 |
| Identity | 1H-NMR |
| Solvents | ethyl acetate |
| Smiles | CN(C1=C2N(C)C=N1)C(N(CCCCC(O)=O)C2=O)=O |
| InChi Key | JDMFPLGXRUJOTC-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) S. Hayashi, et al.: Chem. Pharm. Bull. 24, 1384 (1976), (2) T.A. Bryce, et al.: J. Chromatogr. 344, 397 (1985), (3) G.W. Sullivan, et al.: Infect. Immun. 56, 1722 (1988), (4) M. Fantin, et al.: Eur. J. Pharmacol. 301, 535 (2006), (5) M. Magnusson, et al.: Eur. J. Pharmacol. 290, 581 (2008) |
| InChi | InChI=1S/C12H16N4O4/c1-14-7-13-10-9(14)11(19)16(12(20)15(10)2)6-4-3-5-8(17)18/h7H,3-6H2,1-2H3,(H,17,18) |
| Quantity | 10 mg, 25 mg, Bulk |
