Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder or crystals
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, DMF, ethanol (all 30mg/ml) or chloroform
Documentation
- Safety Data Sheet (SDS)
- CDX M0758 MSDS.pdf
Available from stock
1-(6-Methoxy-2-naphthyl)ethanol
- SKU
- M0758
Category: API's & Intermediates
- Synonyms
- Naproxen Impurity K (Ph.Eur), MNE, &alpha,-(6-Methoxy-2-naphthyl)-ethanol, (±)-1-(6-Methoxy-2-naphthyl)-ethanol, 2-(1-Hydroxyethyl)-6-methoxynaphthalin, 6-Methoxy-?-methyl-2-naphthalinmethanol
- 77301-42-9
- CAS-Number
- C13H14O2
- Molecular Formula
- 202.25
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H302 + H312 + H332 - H413
- Precautionary statements
- P261 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- The metabolite (1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K) is a photo-degradation product from Naproxen which is a non-steroidal anti-inflammatory drug (NSAID) used to in the treatment of pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. Ibuprofen is an anti-inflammatory COX inhibitor. This product can be used as a working standard or secondary analytical reference standard or as an organic building block and intermediate for synthesis.
- Smiles
- C(C)(O)C1=CC2=C(C=C(OC)C=C2)C=C1
- InChi Key
- OUVJWFRUESFCCY-UHFFFAOYSA-N
- References
- (1) A. Ekpe, et al., J. Chromatogr. Sci. 39, 81 (2001) , (2) L. Monser & F. Darghouth, J. Pharma. Biomed. Anal. 32, 1087 (2003) , (3) M. Valero & C Carrillo, J. Photochem. Photobiol. B: Biol. 74, 151 (2004) , (4) M. Isidori, et al., Sci. The Total Env. 348, 93 (2005) , (5) R.S. Reddy, et al., TACL 6, 55 (2016) , (6) N. Cazzaniga, et al., Eur. J. Mass Spectr. 26, 400 (2020)
- InChi
- InChI=1S/C13H14O2/c1-9(14)10-3-4-12-8-13(15-2)6-5-11(12)7-10/h3-9,14H,1-2H3
The metabolite (1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K) is a photo-degradation product from Naproxen which is a non-steroidal anti-inflammatory drug (NSAID) used to in the treatment of pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. Ibuprofen is an anti-inflammatory COX inhibitor. This product can be used as a working standard or secondary analytical reference standard or as an organic building block and intermediate for synthesis.
Additional information
| Synonyms | Naproxen Impurity K (Ph.Eur), MNE, &alpha,-(6-Methoxy-2-naphthyl)-ethanol, (±)-1-(6-Methoxy-2-naphthyl)-ethanol, 2-(1-Hydroxyethyl)-6-methoxynaphthalin, 6-Methoxy-?-methyl-2-naphthalinmethanol |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder or crystals |
| CAS-Number | 77301-42-9 |
| Molecular Formula | C13H14O2 |
| Molecular Weight | 202.25 |
| Identity | 1H-NMR |
| Solvents | DMSO, DMF, ethanol (all 30mg/ml) or chloroform |
| Smiles | C(C)(O)C1=CC2=C(C=C(OC)C=C2)C=C1 |
| InChi Key | OUVJWFRUESFCCY-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H302 + H312 + H332 – H413 |
| Precautionary statements | P261 – P273 – P280 – P301 + P312 – P302 + P352 + P312 – P304 + P340 + P312 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) A. Ekpe, et al., J. Chromatogr. Sci. 39, 81 (2001), (2) L. Monser & F. Darghouth, J. Pharma. Biomed. Anal. 32, 1087 (2003), (3) M. Valero & C Carrillo, J. Photochem. Photobiol. B: Biol. 74, 151 (2004), (4) M. Isidori, et al., Sci. The Total Env. 348, 93 (2005), (5) R.S. Reddy, et al., TACL 6, 55 (2016), (6) N. Cazzaniga, et al., Eur. J. Mass Spectr. 26, 400 (2020) |
| InChi | InChI=1S/C13H14O2/c1-9(14)10-3-4-12-8-13(15-2)6-5-11(12)7-10/h3-9,14H,1-2H3 |
| Quantity | 50 mg, Bulk |
