Available from stock

[10]-Gingerol

SKU: G0198

Category: Phytochemicals

Synonyms: (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone , 10-Gingerol , (S)-[10]-Gingerol; 23513-15-7
CAS-Number: C₂₁H₃₄O₄
Molecular Formula: 350.49
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Light-yellow powder
Identity: 1H-NMR

Properties

Solvents: DMSO (25 mg/ml), DMF (30 mg/ml), ethanol (15 mg/ml), methanol (5 mg/ml)

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: 10-Gingerol is originally found in species of Zingiber. It exhibits antiemetic, anticancer, antioxidative, anti-inflammatory and antibiotic activities. 10-Gingerol increases radical scavenging of superoxide and hydroxyl radicals, inhibits oxidative burst activity and decreases expression of NO and PGE2 in vitro. It exhibits antioxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation. 10-Gingerol also inhibits 5-HT3 receptors. Additionally, 10-gingerol inhibits proliferation in different cancer cells. Shwon to suppresses IL-2-induced proliferation of T lymphocytes. This compound also displays antibacterial efficacy against gram negative bacteria such as Porphyromonas and Prevotella, antifungal and antiparasitic activity.
Smiles: OC1=CC=C(CCC(C[C@@H](O)CCCCCCCCC)=O)C=C1OC
InChi Key: AIULWNKTYPZYAN-SFHVURJKSA-N
References: (1) S. Chrubasik, et al., Phytomedicine 12, 684 (2005) , (2) H. Abdel-Aziz, et al., Eur. J. Pharmacol. 530, 136 (2006) , (3) M. Park, et al., Phytother. Res. 22, 1446 (2008) , (4) C.Y. Chen, et al., Molecules 14, 959 (2009) , (5) S. Dugasani, et al., J. Ethnopharmacol. 127, 515 (2010) , (6) S.C. Ho, et al., Food Chem. 141, 3183 (2013) , (7) M.A. Bakht, et al., Asian Pac. J. Trop. Med. 4, 329 (2014) , (8) M. Bernard, et al., Phytother. Res. 29, 1707 (2015) , (9) M.M. Bernard, et al., Exp. Mol. Pathol. 102, 370 (2017) , (10) F. Zhang, et al., Food Funct. 8, 2635 (2017) (Review) , (11) W. Si, et al., Food Chem. 239, 1117 (2018) , (12) A.M. Fuzer, et al., Anticancer Agents Med. Chem. 19, 645 (2019) , (13) Y.W. Fu, et al., Vet. Parasitol. 265, 74 (2019)

10-Gingerol is originally found in species of Zingiber. It exhibits antiemetic, anticancer, antioxidative, anti-inflammatory and antibiotic activities. 10-Gingerol increases radical scavenging of superoxide and hydroxyl radicals, inhibits oxidative burst activity and decreases expression of NO and PGE2 in vitro. It exhibits antioxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation. 10-Gingerol also inhibits 5-HT3 receptors. Additionally, 10-gingerol inhibits proliferation in different cancer cells. Shwon to suppresses IL-2-induced proliferation of T lymphocytes. This compound also displays antibacterial efficacy against gram negative bacteria such as Porphyromonas and Prevotella, antifungal and antiparasitic activity.

SKU: G0198 Category: Phytochemicals

Additional information

Additional information

Synonyms	(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone, 10-Gingerol, (S)-[10]-Gingerol
Purity	≥98% (HPLC)
Appearance	Light-yellow powder
CAS-Number	23513-15-7
Molecular Formula	C21H34O4
Molecular Weight	350.49
Identity	1H-NMR
Solvents	DMSO (25 mg/ml), DMF (30 mg/ml), ethanol (15 mg/ml), methanol (5 mg/ml)
Smiles	OC1=CC=C(CCC(C[C@@H](O)CCCCCCCCC)=O)C=C1OC
InChi Key	AIULWNKTYPZYAN-SFHVURJKSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) S. Chrubasik, et al., Phytomedicine 12, 684 (2005), (2) H. Abdel-Aziz, et al., Eur. J. Pharmacol. 530, 136 (2006), (3) M. Park, et al., Phytother. Res. 22, 1446 (2008), (4) C.Y. Chen, et al., Molecules 14, 959 (2009), (5) S. Dugasani, et al., J. Ethnopharmacol. 127, 515 (2010), (6) S.C. Ho, et al., Food Chem. 141, 3183 (2013), (7) M.A. Bakht, et al., Asian Pac. J. Trop. Med. 4, 329 (2014), (8) M. Bernard, et al., Phytother. Res. 29, 1707 (2015), (9) M.M. Bernard, et al., Exp. Mol. Pathol. 102, 370 (2017), (10) F. Zhang, et al., Food Funct. 8, 2635 (2017) (Review), (11) W. Si, et al., Food Chem. 239, 1117 (2018), (12) A.M. Fuzer, et al., Anticancer Agents Med. Chem. 19, 645 (2019), (13) Y.W. Fu, et al., Vet. Parasitol. 265, 74 (2019)
Quantity	5 mg, 10 mg, Bulk