Available from stock

1,1′-Didodecyl-3,3,3′,3′-tetramethyl indocarbocyanine perchlorate

SKU: D1022

Category: Fluorescent Detection

Synonyms: DiIC12(3); 84109-08-0
CAS-Number: C₄₇H₇₃N₂.ClO₄
Molecular Formula: 765.55
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99% (HPLC)
Appearance: Dark green-yellow solid or chunks
Identity: 1H-NMR

Properties

Solvents: DMSO or methanol

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and air. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315-H319-H335
Precautionary statements: P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: DiIC12(3) is a lipophilic fluorescent carbocyanine dye used to measure mitochondrial membrane potential. Can be used for neuronal tracing, vascular imaging and cell membrane labeling. It may incorporate into membranes more easily than DiI. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (∼1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane. Spectral Data: Excitation max: ~ 549nm, Emission max: ~564nm (MeOH).
Smiles: CCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O
InChi Key: MPVFAUXPXHGRPQ-UHFFFAOYSA-M
References: (1) P.A. St John, Life Sci. 49, 2013 (1991) , (2) L.S. De Clerck, et al., J. Immunol. Meth. 172, 115 (1994) , (3) S. Mukherjee, et al., J. Cell Biol. 144, 1271 (1999) , (4) L.M. Loura, et al., Biochim. Biophys. Acta 1467, 101 (2000) , (5) M.J. Wirth, et al., J. Chromatogr. A. 1034, 69 (2004) , (6) A.F. Na, et al., J. Pediatr. Surg. 42, 1566 (2007) , (7) E. Braeken, et al., Chem. Phys. Lett. 472, 48 (2009) , (8) J.J. Strouse, et al., Anal. Biochem. 437, 77 (2013)
InChi: InChI=1S/C47H73N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-29-38-48-42-34-27-25-32-40(42)46(3,4)44(48)36-31-37-45-47(5,6)41-33-26-28-35-43(41)49(45)39-30-24-22-20-18-16-14-12-10-8-2,2-1(3,4)5/h25-28,31-37H,7-24,29-30,38-39H2,1-6H3,(H,2,3,4,5)/q+1,/p-1

DiIC12(3) is a lipophilic fluorescent carbocyanine dye used to measure mitochondrial membrane potential. Can be used for neuronal tracing, vascular imaging and cell membrane labeling. It may incorporate into membranes more easily than DiI. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (∼1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane. Spectral Data: Excitation max: ~ 549nm, Emission max: ~564nm (MeOH).

SKU: D1022 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	DiIC12(3)
Purity	≥99% (HPLC)
Appearance	Dark green-yellow solid or chunks
CAS-Number	84109-08-0
Molecular Formula	C47H73N2.ClO4
Molecular Weight	765.55
Identity	1H-NMR
Solvents	DMSO or methanol
Smiles	CCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O
InChi Key	MPVFAUXPXHGRPQ-UHFFFAOYSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and air. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) P.A. St John, Life Sci. 49, 2013 (1991), (2) L.S. De Clerck, et al., J. Immunol. Meth. 172, 115 (1994), (3) S. Mukherjee, et al., J. Cell Biol. 144, 1271 (1999), (4) L.M. Loura, et al., Biochim. Biophys. Acta 1467, 101 (2000), (5) M.J. Wirth, et al., J. Chromatogr. A. 1034, 69 (2004), (6) A.F. Na, et al., J. Pediatr. Surg. 42, 1566 (2007), (7) E. Braeken, et al., Chem. Phys. Lett. 472, 48 (2009), (8) J.J. Strouse, et al., Anal. Biochem. 437, 77 (2013)
InChi	InChI=1S/C47H73N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-29-38-48-42-34-27-25-32-40(42)46(3,4)44(48)36-31-37-45-47(5,6)41-33-26-28-35-43(41)49(45)39-30-24-22-20-18-16-14-12-10-8-2,2-1(3,4)5/h25-28,31-37H,7-24,29-30,38-39H2,1-6H3,(H,2,3,4,5)/q+1,/p-1
Quantity	50 mg, 100 mg, 250 mg, Bulk