Specifications
- Purity
- ≥95%
- Identity
- 1H-NMR
- Appearance
- White to off-white powder
Properties
- Solvents
- chloroform
Downloads
- Safety Data Sheet
- CDX D0489 MSDS.pdf
Available from stock
2,5-Dioxopyrrolidin-1-yl propanoate
- SKU
- D0489
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- N-(Propionyloxy)succinimide , N-succinimidyl propionate , NSP , Propionyl-Osu , 1-(1-Oxopropoxy)-2,5-pyrrolidinedione
- 30364-55-7
- CAS-Number
- C7H9NO4
- Molecular Formula
- 171.15
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Long Term Storage
- +4°C
- Short Term Storage
- RT
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P332+P313, P337+P313, P362, P403+P233, P405, P501
- Hazard statements
- H315, H319, H335
- Description
- Biochemical for proteomics research use. Amine-specific protein-acylating agent. Used for derivatization of biogenic amines for hplc analysis. Recent stuides use this agent for derivatization of histone post-translational modifications. The compound has been used in several studies describing this well established reagent for the introduction of a tritium label into proteins or other biologicals. The retrograde transport of protein components of sciatic nerve axons has been demonstrated by direct labelling of the protein using [3H]NSP in vivo.
- InChi
- InChI=1S/C7H9NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2-4H2,1H3
- References
- (1) J.C. Hedreen & G.C. Holm, Brain Res. Bull. 7, 665 (1981) , (2) Y.S. Tang, J. Labelled Comp. Radiopharm. 20, 277 (1982) , (3) U. Kummer, Meth. Enzymol. 121, 670 (1986) , (4) R. Liao, et al., Anal. Chem. 85, 2253 (2013) , (5) J.Chen, et al., Anal. Chim. Acta 886, 107 (2015)
- InChi Key
- AASBXERNXVFUEJ-UHFFFAOYSA-N
- Smiles
- CCC(ON1C(CCC1=O)=O)=O
Biochemical for proteomics research use. Amine-specific protein-acylating agent. Used for derivatization of biogenic amines for hplc analysis. Recent stuides use this agent for derivatization of histone post-translational modifications. The compound has been used in several studies describing this well established reagent for the introduction of a tritium label into proteins or other biologicals. The retrograde transport of protein components of sciatic nerve axons has been demonstrated by direct labelling of the protein using [3H]NSP in vivo.
Additional information
| Synonyms | N-(Propionyloxy)succinimide, N-succinimidyl propionate, NSP, Propionyl-Osu, 1-(1-Oxopropoxy)-2,5-pyrrolidinedione |
|---|---|
| Purity | ≥95% |
| Appearance | White to off-white powder |
| CAS-Number | 30364-55-7 |
| Molecular Formula | C7H9NO4 |
| Molecular Weight | 171.15 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Smiles | CCC(ON1C(CCC1=O)=O)=O |
| InChi Key | AASBXERNXVFUEJ-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P332+P313, P337+P313, P362, P403+P233, P405, P501 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) J.C. Hedreen & G.C. Holm, Brain Res. Bull. 7, 665 (1981), (2) Y.S. Tang, J. Labelled Comp. Radiopharm. 20, 277 (1982), (3) U. Kummer, Meth. Enzymol. 121, 670 (1986), (4) R. Liao, et al., Anal. Chem. 85, 2253 (2013), (5) J.Chen, et al., Anal. Chim. Acta 886, 107 (2015) |
| InChi | InChI=1S/C7H9NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2-4H2,1H3 |
| Quantity | 250 mg, 500 mg, Bulk |
