Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (slightly), methanol (slightly)
- Melting Point
- 191-193°C
Documentation
- Safety Data Sheet (SDS)
- CDX H0030 MSDS.pdf
Available from stock
3-cis-Hydroxyglibenclamide
- SKU
- H0030
Category: API's & Intermediates
- Synonyms
- 3-cis-Hydroxycyclohexyl glyburide , cis-3-Hydroxyglyburide
- 23074-02-4
- CAS-Number
- C23H28ClN3O6S
- Molecular Formula
- 510.00
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P280-P305 + P351 + P338-P337 + P313
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.
- Smiles
- COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)N[C@H]3CCC[C@H](C3)O
- InChi Key
- VFBAJFAMXTVSQA-ZWKOTPCHSA-N
- References
- (1) W. Heptner, et al. , Pharmaceut. Res. 5, 215 (1984) , (2) T. Rydberg, et al. , J. Chromatogr. 564, 223 (1991) , (3) T. Rydberg, et al. , Diabetes Care 17, 1026 (1994) , (4) T. Rydberg, et al. , J. Clin. Pharm. Ther. 20, 283 (1995) , (5) T. Rydberg, et al. , Br. J. Clin. Pharm. 43, 373 (1997)
- InChi
- InChI=1S/C23H28ClN3O6S/c1-33-21-10-7-16(24)13-20(21)22(29)25-12-11-15-5-8-19(9-6-15)34(31,32)27-23(30)26-17-3-2-4-18(28)14-17/h5-10,13,17-18,28H,2-4,11-12,14H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18+/m0/s1
M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.
Additional information
| Synonyms | 3-cis-Hydroxycyclohexyl glyburide, cis-3-Hydroxyglyburide |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 23074-02-4 |
| Molecular Formula | C23H28ClN3O6S |
| Molecular Weight | 510.00 |
| Identity | 1H-NMR |
| Solvents | DMSO (slightly), methanol (slightly) |
| Melting Point | 191-193°C |
| Smiles | COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)N[C@H]3CCC[C@H](C3)O |
| InChi Key | VFBAJFAMXTVSQA-ZWKOTPCHSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P305 + P351 + P338-P337 + P313 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) W. Heptner, et al., Pharmaceut. Res. 5, 215 (1984), (2) T. Rydberg, et al., J. Chromatogr. 564, 223 (1991), (3) T. Rydberg, et al., Diabetes Care 17, 1026 (1994), (4) T. Rydberg, et al., J. Clin. Pharm. Ther. 20, 283 (1995), (5) T. Rydberg, et al., Br. J. Clin. Pharm. 43, 373 (1997) |
| InChi | InChI=1S/C23H28ClN3O6S/c1-33-21-10-7-16(24)13-20(21)22(29)25-12-11-15-5-8-19(9-6-15)34(31,32)27-23(30)26-17-3-2-4-18(28)14-17/h5-10,13,17-18,28H,2-4,11-12,14H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18+/m0/s1 |
| Quantity | 1 mg, 5 mg, Bulk |
