Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- White to light brown powder
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform, 1N sodium hydroxide (25 mg/ml)
- Melting Point
- 158-161 °C (lit.)
Available from stock
3-Fluorophthalic anhydride
- SKU
- F0148
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- 4-Fluoro-2-benzofuran-1,3-dione
- 652-39-1
- CAS-Number
- C8H3FO3
- Molecular Formula
- 166.11
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- RT
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Hazard statements
- H315-H317-H319-H335
- Precautionary statements
- P261-P280-P305 + P351 + P338
- GHS Symbol
- GHS07
- Transportation
- Not dangerous goods
- Description
- Building block for synthesis. 3-Fluorophthalic anhydride is a useful fluorinated building block for the preparation of various compounds of interest in pharmaceutcials and agrochemicals.
- Smiles
- FC1=C(C(OC2=O)=O)C2=CC=C1
- InChi Key
- WWJAZKZLSDRAIV-UHFFFAOYSA-N
- References
- (1) M.H. Norman, et al., J. Med. Chem. 39, 1172 (1996) , (2) X. Collin, et al., Eur. J. Med. Chem. 36, 639 (2001) , (3) M. Tohnishi, et al., J. Pestic. Sci. 30, 354 (2005) , (4) C.G. Thomson, et al., Bioorg. Med. Chem. Lett. 16, 1388 (2006) , (5) S. Li, et al., Bioorg. Med. Chem. Lett. 17, 1646 (2007) , (6) X. Chen, et al., J. Antibiot. 64, 563 (2011) , (7) K. Yang, et al., Bioorg. Med. Chem. Lett. 28, 2493 (2018)
- InChi
- InChI=1S/C8H3FO3/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3H
Building block for synthesis. 3-Fluorophthalic anhydride is a useful fluorinated building block for the preparation of various compounds of interest in pharmaceutcials and agrochemicals.
Additional information
| Synonyms | 4-Fluoro-2-benzofuran-1,3-dione |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | White to light brown powder |
| CAS-Number | 652-39-1 |
| Molecular Formula | C8H3FO3 |
| Molecular Weight | 166.11 |
| Identity | 1H-NMR |
| Solvents | chloroform, 1N sodium hydroxide (25 mg/ml) |
| Melting Point | 158-161 °C (lit.) |
| Smiles | FC1=C(C(OC2=O)=O)C2=CC=C1 |
| InChi Key | WWJAZKZLSDRAIV-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Hazard statements | H315-H317-H319-H335 |
| Precautionary statements | P261-P280-P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Transportation | Not dangerous goods |
| References | (1) M.H. Norman, et al., J. Med. Chem. 39, 1172 (1996), (2) X. Collin, et al., Eur. J. Med. Chem. 36, 639 (2001), (3) M. Tohnishi, et al., J. Pestic. Sci. 30, 354 (2005), (4) C.G. Thomson, et al., Bioorg. Med. Chem. Lett. 16, 1388 (2006), (5) S. Li, et al., Bioorg. Med. Chem. Lett. 17, 1646 (2007), (6) X. Chen, et al., J. Antibiot. 64, 563 (2011), (7) K. Yang, et al., Bioorg. Med. Chem. Lett. 28, 2493 (2018) |
| InChi | InChI=1S/C8H3FO3/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3H |
| Quantity | 5 g, 25 g, Bulk |
