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    3-Hydroxy-hexanoyl-L-homoserine lactone

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      3-Hydroxy-hexanoyl-L-homoserine lactone

      SKU
      H0083

      Category: Quorum Sensing

      Synonyms
      3OH-C6-HSL S/RS
      192883-16-2
      CAS-Number
      C10H17NO4
      Molecular Formula
      215.25
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (NMR)
      Appearance
      White to pink powder
      Identity
      1H-NMR

      Properties

      Solvents
      ethanol, methanol, DMF, DMSO or water (poorly)
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H302
      Precautionary statements
      P280
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      3-Hydroxy-hexanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
      Smiles
      O=C1[C@@H](NC(CC(O)CCC)=O)CCO1
      InChi Key
      CRCIHGGZGGATGM-MQWKRIRWSA-N
      References
      (1) M. Teplitski, et al.: Arch. Microbiol. 180, 494 (2003) , (2) S.R. Kahne, et al.: Appl. Env. Microbiol. 73, 7443 (2007) , (3) V. Thiel, et al.: ChemBioChem 10, 1861 (2009) , (4) C.A. Ortori, et al.: Anal. Bioanal. Chem. 399, 839 (2011)
      InChi
      InChI=1S/C10H17NO4/c1-2-3-7(12)6-9(13)11-8-4-5-15-10(8)14/h7-8,12H,2-6H2,1H3,(H,11,13)/t7?,8-/m0/s1

      3-Hydroxy-hexanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

      SKU: H0083 Category: Quorum Sensing
      • Additional information

      Additional information

      Synonyms

      3OH-C6-HSL S/RS

      Purity

      ≥98% (NMR)

      Appearance

      White to pink powder

      CAS-Number

      192883-16-2

      Molecular Formula

      C10H17NO4

      Molecular Weight

      215.25

      Identity

      1H-NMR

      Solvents

      ethanol, methanol, DMF, DMSO or water (poorly)

      Smiles

      O=C1[C@@H](NC(CC(O)CCC)=O)CCO1

      InChi Key

      CRCIHGGZGGATGM-MQWKRIRWSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H302

      Precautionary statements

      P280

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) M. Teplitski, et al.: Arch. Microbiol. 180, 494 (2003), (2) S.R. Kahne, et al.: Appl. Env. Microbiol. 73, 7443 (2007), (3) V. Thiel, et al.: ChemBioChem 10, 1861 (2009), (4) C.A. Ortori, et al.: Anal. Bioanal. Chem. 399, 839 (2011)

      InChi

      InChI=1S/C10H17NO4/c1-2-3-7(12)6-9(13)11-8-4-5-15-10(8)14/h7-8,12H,2-6H2,1H3,(H,11,13)/t7?,8-/m0/s1

      Quantity

      5 mg, 25 mg, Bulk

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