Available from stock

3,3′-Diheptyloxacarbocyanine iodide

SKU: D0994

Category: Fluorescent Detection

Synonyms: DiOC7(3), D 378; 53213-83-5
CAS-Number: _x₀₀₀D_C₃₁H₄₁N₂O₂ I
Molecular Formula: 600.58
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (HPLC)
Appearance: Coral to orange powder
Identity: 1H-NMR

Properties

Solvents: DMSO or methanol
Fluorescence: λex 484 nm, λem 504 nm in methanol

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and air. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H335, H319, H360
Precautionary statements: P201, P281, P308+P313, P202
GHS Symbol: GHS07+GHS08
Signal word: Danger
Transportation: Not dangerous goods

Description: DiOC7(3) is a fluorescent carbocyanine dye used to measure mitochondrial membrane potential and labeling membranes (particularly in bacteria or yeast). It can be used for flow cytometry and fluorescent microscopy. It intercalates into membranes and responds to changes in membrane potential, making it useful for antibiotic screening, efflux activity studies, and cell viability assessments. Used in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. Spectral Data: Excitation max: ~ 484nm, Emission max: ~500-510nm (accord. Lit).
Smiles: C(CCCCCC)N1C=2C(OC1=CC=CC3=[N+](CCCCCCC)C=4C(O3)=CC=CC4)=CC=CC2.[I-]
InChi Key: ANJZLSIIEGUCQL-UHFFFAOYSA-M
References: (1) P.J. Sims, et al., Biochem. 13, 3315 (1974) , (2) P.L. Olive & R.E. Durand, Cytometry 8, 571 (1987) , (3) D.H. Wiegand & P. Vanysek, Appl. Spectrosc. 42, 958 (1988) , (4) M.J. Trotter, et al., Br. J. Cancer 59, 706 (1989) , (5) R.M. Wadkins & P.J. Houghton, Biochem. 34, 3858 (1995)
InChi: InChI=1S/C31H41N2O2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31,/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3,1H/q+1,/p-1

DiOC7(3) is a fluorescent carbocyanine dye used to measure mitochondrial membrane potential and labeling membranes (particularly in bacteria or yeast). It can be used for flow cytometry and fluorescent microscopy. It intercalates into membranes and responds to changes in membrane potential, making it useful for antibiotic screening, efflux activity studies, and cell viability assessments. Used in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. Spectral Data: Excitation max: ~ 484nm, Emission max: ~500-510nm (accord. Lit).

SKU: D0994 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	DiOC7(3), D 378
Purity	≥97% (HPLC)
Appearance	Coral to orange powder
CAS-Number	53213-83-5
Molecular Formula	_x000D_C31H41N2O2 I
Molecular Weight	600.58
Identity	1H-NMR
Solvents	DMSO or methanol
Fluorescence	λex 484 nm, λem 504 nm in methanol
Smiles	C(CCCCCC)N1C=2C(OC1=CC=CC3=[N+](CCCCCCC)C=4C(O3)=CC=CC4)=CC=CC2.[I-]
InChi Key	ANJZLSIIEGUCQL-UHFFFAOYSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and air. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H335, H319, H360
Precautionary statements	P201, P281, P308+P313, P202
GHS Symbol	GHS07+GHS08
Signal word	Danger
Transportation	Not dangerous goods
References	(1) P.J. Sims, et al., Biochem. 13, 3315 (1974), (2) P.L. Olive & R.E. Durand, Cytometry 8, 571 (1987), (3) D.H. Wiegand & P. Vanysek, Appl. Spectrosc. 42, 958 (1988), (4) M.J. Trotter, et al., Br. J. Cancer 59, 706 (1989), (5) R.M. Wadkins & P.J. Houghton, Biochem. 34, 3858 (1995)
InChi	InChI=1S/C31H41N2O2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31,/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3,1H/q+1,/p-1
Quantity	50 mg, 100 mg, 250 mg, Bulk