Specifications
- Purity
- ≥98% (NMR)
- Appearance
- Solid
- Identity
- 1H-NMR
Properties
- Solvents
- methanol, DMSO, DMF
- Melting Point
- 288 °C
- Fluorescence
- λex 556 nm, λem 575 nm in methanol
Available from stock
3,3′-Dipropylthiacarbocyanine iodide
- SKU
- D0007
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- DiSC(3)(3)
- 53336-12-2
- CAS-Number
- C23H25IN2S2
- Molecular Formula
- 520.49
- Molecular Weight
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) can inhibit respiration and may therefore be relatively cytotoxic. 3,3'-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method. Selected applications are: Calcium channels and other ion transport systems, mitochondrial activity, neurons and brain tissue, membrane potential in intact yeast cells
- Smiles
- [I-].CCCN1C(SC2=C1C=CC=C2)=C/C=C/C1=[N+](CCC)C2=C(S1)C=CC=C2
- InChi Key
- JGTCEHAVVINOPG-UHFFFAOYSA-M
- References
- (1) D. Gaskova et al.: Biochem. Biophys. Res. Comm. 354(3), 814 (2007) , (2) D. Gaskova et al.: Int. J. Biochem. Cell Biol. 34(8), 931 (2002) , (3) H. Amlal et al.: M. Bichara: J. Biol. Chem. 269, 21962 (1994) , (4) H.W. van Veen et al.: Biol. Chem. 269, 29509 (1994) , (5) L. Hunyady et al.: Am. J. Physiol. 266, C67 (1994)
- InChi
- InChI=1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23
Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) can inhibit respiration and may therefore be relatively cytotoxic. 3,3′-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method. Selected applications are: Calcium channels and other ion transport systems, mitochondrial activity, neurons and brain tissue, membrane potential in intact yeast cells
Additional information
| Synonyms | DiSC(3)(3) |
|---|---|
| Purity | ≥98% (NMR) |
| Appearance | Solid |
| CAS-Number | 53336-12-2 |
| Molecular Formula | C23H25IN2S2 |
| Molecular Weight | 520.49 |
| Identity | 1H-NMR |
| Solvents | methanol, DMSO, DMF |
| Melting Point | 288 °C |
| Fluorescence | λex 556 nm, λem 575 nm in methanol |
| Smiles | [I-].CCCN1C(SC2=C1C=CC=C2)=C/C=C/C1=[N+](CCC)C2=C(S1)C=CC=C2 |
| InChi Key | JGTCEHAVVINOPG-UHFFFAOYSA-M |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) D. Gaskova et al.: Biochem. Biophys. Res. Comm. 354(3), 814 (2007), (2) D. Gaskova et al.: Int. J. Biochem. Cell Biol. 34(8), 931 (2002), (3) H. Amlal et al.: M. Bichara: J. Biol. Chem. 269, 21962 (1994), (4) H.W. van Veen et al.: Biol. Chem. 269, 29509 (1994), (5) L. Hunyady et al.: Am. J. Physiol. 266, C67 (1994) |
| InChi | InChI=1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23 |
| Quantity | 250 mg, 500 mg, Bulk |
