Available from stock

4-Aminobenzamidine dihydrochloride

SKU: A0920

Category: Fluorescent Detection

Synonyms: 4-ABA, p-Aminobenzamidine dihydrochloride; 2498-50-2
CAS-Number: C₇H₉N₃·₂HCl
Molecular Formula: 208.09
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99% (TLC)
Appearance: Off-white powder
Identity: 1H-NMR

Properties

Solvents: water
Melting Point: 291 °C

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: 4-Aminobenzamidine dihydrochloride can be used as a building block in organic synthesis as well as for investigating enzyme kinetics. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes. This benzamidine derivative is a selective and potent serine protease inhibitors. It functions as a reversible inhibitor of enzymes and ion transporters by binding to their active sites. By doing so, it hinders their interaction with substrates, consequently impeding their activity.
Smiles: C(=N)(N)C1=CC=C(N)C=C1.Cl
InChi Key: GHEHNICLPWTXJC-UHFFFAOYSA-N
References: (1) S.A.Beyler & L.J. Zaneveld, J. Reprod. Fertil. 66, 425 (1982) , (2) D.M. Monroe, et al., Anal. Biochem. 172, 427 (1988) , (3) S. Khamlichi, et al., J. Chromatogr. 510, 123 (1990) , (4) S. Krishnaswamy, et al., J. Biol. Chem. 267, 26110 (1992) , (5) F. Dudouit, et al., J. Heterocyc. Chem. 38, 755 (2001) , (6) M.F. Gouzy, et al., Biomaterials 25, 3493 (2004) , (7) S.G. De-Simone, et al., J. Chromatogr. B. Anal. Technol. Biomed. Life Sci. 822, 1 (2005) , (8) E.I. Klimova, et al., Molecules 19, 41 (2013)
InChi: InChI=1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10,,/h1-4H,8H2,(H3,9,10),2*1H

4-Aminobenzamidine dihydrochloride can be used as a building block in organic synthesis as well as for investigating enzyme kinetics. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes. This benzamidine derivative is a selective and potent serine protease inhibitors. It functions as a reversible inhibitor of enzymes and ion transporters by binding to their active sites. By doing so, it hinders their interaction with substrates, consequently impeding their activity.

SKU: A0920 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	4-ABA, p-Aminobenzamidine dihydrochloride
Purity	≥99% (TLC)
Appearance	Off-white powder
CAS-Number	2498-50-2
Molecular Formula	C7H9N3·2HCl
Molecular Weight	208.09
Identity	1H-NMR
Solvents	water
Melting Point	291 °C
Smiles	C(=N)(N)C1=CC=C(N)C=C1.Cl
InChi Key	GHEHNICLPWTXJC-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) S.A.Beyler & L.J. Zaneveld, J. Reprod. Fertil. 66, 425 (1982), (2) D.M. Monroe, et al., Anal. Biochem. 172, 427 (1988), (3) S. Khamlichi, et al., J. Chromatogr. 510, 123 (1990), (4) S. Krishnaswamy, et al., J. Biol. Chem. 267, 26110 (1992), (5) F. Dudouit, et al., J. Heterocyc. Chem. 38, 755 (2001), (6) M.F. Gouzy, et al., Biomaterials 25, 3493 (2004), (7) S.G. De-Simone, et al., J. Chromatogr. B. Anal. Technol. Biomed. Life Sci. 822, 1 (2005), (8) E.I. Klimova, et al., Molecules 19, 41 (2013)
InChi	InChI=1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10,,/h1-4H,8H2,(H3,9,10),2*1H
Quantity	5 g, 25 g, Bulk
cdx-Emission max.	359.0 ± 5.0 nm