Available from stock

4-Epitetracycline ammmonium salt

SKU: E0592

Category: Antibiotics

Synonyms: ETC, Ammonium Quatrimycin, 4-epi-Tetracycline ammonium salt; 16505-45-6
CAS-Number: C₂₂H₂₇N₃O₈
Molecular Formula: 461.47
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Green to grey solid
Identity: 1H-NMR

Properties

Solvents: DMSO

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315 - H319 - H335 - H361fd
Precautionary statements: P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
GHS Symbol: GHS07+GHS08
Signal word: Warning
Transportation: Not dangerous goods

Description: Tetracycline is a broad-spectrum antibacterial and selection agent. 4-Epitetracycline ammonium salt is a salt form of 4-epitetracycline, a derivative of the antibiotic tetracycline. It is produced when tetracycline undergoes an epimerization. Under acid conditions, tetracycline undergoes a reversible epimerization at the fourth carbon, producing a mixture of tetracycline and 4-Epitetracycline. 4-Epitetracycline is a metabolite/impurity derived from the degradation of tetracycline and has been shown to display reduced antibiotic activity. This product can be used as analytical reference compound.
Smiles: O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(O)(C)C3CC2C(C1O)N(C)C.N
InChi Key: MFBAAOIEZLISSS-DXDJYCPMSA-N
References: (1) N. Muhammad & J.A. Bodnar, J. Pharm. Sci. 69, 928 (1980) , (2) A. Jia, et al., J. Chromatogr. A 1216, 4655 (2009) , (3) E.-R.E. Mojica, et al., J. Fluoresc. 24, 1183 (2014) , (4) S. Long, et al., Chemosphere 246, 125681 (2020)
InChi: InChI=1S/C22H24N2O8.H3N/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28,/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30),1H3/t9-,10-,15+,21+,22-,/m0./s1

Tetracycline is a broad-spectrum antibacterial and selection agent. 4-Epitetracycline ammonium salt is a salt form of 4-epitetracycline, a derivative of the antibiotic tetracycline. It is produced when tetracycline undergoes an epimerization. Under acid conditions, tetracycline undergoes a reversible epimerization at the fourth carbon, producing a mixture of tetracycline and 4-Epitetracycline. 4-Epitetracycline is a metabolite/impurity derived from the degradation of tetracycline and has been shown to display reduced antibiotic activity. This product can be used as analytical reference compound.

SKU: E0592 Category: Antibiotics

Additional information

Additional information

Synonyms	ETC, Ammonium Quatrimycin, 4-epi-Tetracycline ammonium salt
Purity	≥98% (HPLC)
Appearance	Green to grey solid
CAS-Number	16505-45-6
Molecular Formula	C22H27N3O8
Molecular Weight	461.47
Identity	1H-NMR
Solvents	DMSO
Smiles	O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(O)(C)C3CC2C(C1O)N(C)C.N
InChi Key	MFBAAOIEZLISSS-DXDJYCPMSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315 – H319 – H335 – H361fd
Precautionary statements	P201 – P202 – P261 – P302 + P352 – P305 + P351 + P338 – P308 + P313
GHS Symbol	GHS07+GHS08
Signal word	Warning
Transportation	Not dangerous goods
References	(1) N. Muhammad & J.A. Bodnar, J. Pharm. Sci. 69, 928 (1980), (2) A. Jia, et al., J. Chromatogr. A 1216, 4655 (2009), (3) E.-R.E. Mojica, et al., J. Fluoresc. 24, 1183 (2014), (4) S. Long, et al., Chemosphere 246, 125681 (2020)
InChi	InChI=1S/C22H24N2O8.H3N/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28,/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30),1H3/t9-,10-,15+,21+,22-,/m0./s1
Quantity	100 mg, 250 mg, 500 mg, Bulk