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    4-trans-Hydroxy-glibenclamide

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    4-trans-Hydroxy-glibenclamide

    SKU
    H0027

    Category: API's & Intermediates

    Synonyms
    4-trans-Hydroxycyclohexyl glyburide , 4-trans-Hydroxyglyburide
    23155-00-2
    CAS-Number
    C23H28ClN3O6S
    Molecular Formula
    510.00
    Molecular Weight

    • Product Data
    • Handling
    • Safety Information
    • Details

    Specifications

    Purity
    ≥97% (HPLC)
    Identity
    1H-NMR
    Appearance
    White crystalline powder

    Properties

    Melting Point
    163 - 164 °C
    Solvents
    DMSO, methanol

    Downloads

    Safety Data Sheet
    CDX H0027 MSDS.pdf
    Handling Advice
    Protect from light and moisture.
    Use / Stability
    Stable for at least 2 years after receipt when stored at -20°C.
    Long Term Storage
    -20° C
    Short Term Storage
    +4°C
    Shipping
    AMBIENT
    Transportation
    Not dangerous goods
    Signal word
    Warning
    GHS Symbol
    GHS07
    Precautionary statements
    P280-P305 + P351 + P338-P337 + P313
    Hazard statements
    H315-H319-H335
    Description
    A key active metabolite of the antidiabetic compound glyburide.
    InChi
    InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-
    References
    (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994) , (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995) , (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998)
    InChi Key
    IUWSGCQEWOOQDN-IYARVYRRSA-N
    Smiles
    O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O

    A key active metabolite of the antidiabetic compound glyburide.

    SKU: H0027 Category: API's & Intermediates
    • Additional information

    Additional information

    Synonyms

    4-trans-Hydroxycyclohexyl glyburide, 4-trans-Hydroxyglyburide

    Purity

    ≥97% (HPLC)

    Appearance

    White crystalline powder

    CAS-Number

    23155-00-2

    Molecular Formula

    C23H28ClN3O6S

    Molecular Weight

    510.00

    Identity

    1H-NMR

    Solvents

    DMSO, methanol

    Melting Point

    163 – 164 °C

    Smiles

    O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O

    InChi Key

    IUWSGCQEWOOQDN-IYARVYRRSA-N

    Shipping

    AMBIENT

    Short Term Storage

    +4°C

    Long Term Storage

    -20° C

    Handling Advice

    Protect from light and moisture.

    Use / Stability

    Stable for at least 2 years after receipt when stored at -20°C.

    Hazard statements

    H315-H319-H335

    Precautionary statements

    P280-P305 + P351 + P338-P337 + P313

    GHS Symbol

    GHS07

    Signal word

    Warning

    Transportation

    Not dangerous goods

    References

    (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994), (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995), (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998)

    InChi

    InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-

    Quantity

    1 mg, 5 mg, Bulk

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