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    4-trans-Hydroxy-glibenclamide

    Available from stock

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      4-trans-Hydroxy-glibenclamide

      SKU
      H0027

      Category: API's & Intermediates

      Synonyms
      4-trans-Hydroxycyclohexyl glyburide , 4-trans-Hydroxyglyburide
      23155-00-2
      CAS-Number
      C23H28ClN3O6S
      Molecular Formula
      510.00
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥97% (HPLC)
      Appearance
      White crystalline powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO, methanol
      Melting Point
      163 - 164 °C

      Documentation

      Safety Data Sheet (SDS)
      CDX H0027 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20° C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315-H319-H335
      Precautionary statements
      P280-P305 + P351 + P338-P337 + P313
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      A key active metabolite of the antidiabetic compound glyburide.
      Smiles
      O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O
      InChi Key
      IUWSGCQEWOOQDN-IYARVYRRSA-N
      References
      (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994) , (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995) , (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998)
      InChi
      InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-

      A key active metabolite of the antidiabetic compound glyburide.

      SKU: H0027 Category: API's & Intermediates
      • Additional information

      Additional information

      Synonyms

      4-trans-Hydroxycyclohexyl glyburide, 4-trans-Hydroxyglyburide

      Purity

      ≥97% (HPLC)

      Appearance

      White crystalline powder

      CAS-Number

      23155-00-2

      Molecular Formula

      C23H28ClN3O6S

      Molecular Weight

      510.00

      Identity

      1H-NMR

      Solvents

      DMSO, methanol

      Melting Point

      163 – 164 °C

      Smiles

      O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O

      InChi Key

      IUWSGCQEWOOQDN-IYARVYRRSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20° C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315-H319-H335

      Precautionary statements

      P280-P305 + P351 + P338-P337 + P313

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994), (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995), (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998)

      InChi

      InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-

      Quantity

      1 mg, 5 mg, Bulk

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