Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White crystalline powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, methanol
- Melting Point
- 163 - 164 °C
Documentation
- Safety Data Sheet (SDS)
- CDX H0027 MSDS.pdf
Available from stock
4-trans-Hydroxy-glibenclamide
- SKU
- H0027
Category: API's & Intermediates
- Synonyms
- 4-trans-Hydroxycyclohexyl glyburide , 4-trans-Hydroxyglyburide
- 23155-00-2
- CAS-Number
- C23H28ClN3O6S
- Molecular Formula
- 510.00
- Molecular Weight
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20° C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P280-P305 + P351 + P338-P337 + P313
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- A key active metabolite of the antidiabetic compound glyburide.
- Smiles
- O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O
- InChi Key
- IUWSGCQEWOOQDN-IYARVYRRSA-N
- References
- (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994) , (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995) , (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998)
- InChi
- InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-
A key active metabolite of the antidiabetic compound glyburide.
Additional information
| Synonyms | 4-trans-Hydroxycyclohexyl glyburide, 4-trans-Hydroxyglyburide |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White crystalline powder |
| CAS-Number | 23155-00-2 |
| Molecular Formula | C23H28ClN3O6S |
| Molecular Weight | 510.00 |
| Identity | 1H-NMR |
| Solvents | DMSO, methanol |
| Melting Point | 163 – 164 °C |
| Smiles | O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O |
| InChi Key | IUWSGCQEWOOQDN-IYARVYRRSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20° C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P305 + P351 + P338-P337 + P313 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) T. Rydberg, et al., Diaβ Care 17, 1026 (1994), (2) T. Rydberg, et al., J. Clin. Pharm. Therap. 20, 283 (1995), (3) A. Jonsson, et al., Eur. J. Clin. Pharmacol. 53, 429 (1998) |
| InChi | InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18- |
| Quantity | 1 mg, 5 mg, Bulk |
