Specifications
- Purity
- ≥95% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Grey-brown powder
Properties
- Solvents
- water
Downloads
- Safety Data Sheet
- CDX H0026 MSDS.pdf
Available from stock
5,7-Dihydroxytryptamine hydrobromide
- SKU
- H0026
Category: API's & Intermediates
- Synonyms
- 5,7-DHT , 3-(2-Aminoethyl)-1H-indole-5,7-diol
- 31363-74-3 (free b
- CAS-Number
- C10H12N2O2 . HBr
- Molecular Formula
- 192.2 . 80.9
- Molecular Weight
- Short Term Storage
- +4°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- -20°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Description
- Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
- InChi
- InChI=1S/C10H12N2O2.BrH/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14
- References
- (1) H.G. Baumgarten, et al.: Acta Physiol. Scand. Suppl. 391, 1 (1973) , (2) B. Allis & G. Cohen , Eur. J. Pharmacol. 43, 269 (1977) , (3) K. Fuxe, et al.: Ann. N. Y. Acad. Sci. 305, 346 (1978) , (4) M.Z. Wrona, et al.: J. Med. Chem. 29, 499 (1986) , (5) A.K. Sinhababu & R.T. Borchardt , Neurochem. Int. 12, 273 (1988) , (6) K.T. Finnegan, et al.: Brain. Res. 496, 251 (1989) , (7) H. Franke,et al.: Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)
- InChi Key
- KVRZGCBQKAJSBN-UHFFFAOYSA-N
- Smiles
- OC1=C(NC=C2CC[NH3+])C2=CC(O)=C1.[Br-]
Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
Additional information
| Synonyms | 5,7-DHT, 3-(2-Aminoethyl)-1H-indole-5,7-diol |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | Grey-brown powder |
| CAS-Number | 31363-74-3 (free b |
| Molecular Formula | C10H12N2O2 . HBr |
| Molecular Weight | 192.2 . 80.9 |
| Identity | 1H-NMR |
| Solvents | water |
| Smiles | OC1=C(NC=C2CC[NH3+])C2=CC(O)=C1.[Br-] |
| InChi Key | KVRZGCBQKAJSBN-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) H.G. Baumgarten, et al.: Acta Physiol. Scand. Suppl. 391, 1 (1973), (2) B. Allis & G. Cohen, Eur. J. Pharmacol. 43, 269 (1977), (3) K. Fuxe, et al.: Ann. N. Y. Acad. Sci. 305, 346 (1978), (4) M.Z. Wrona, et al.: J. Med. Chem. 29, 499 (1986), (5) A.K. Sinhababu & R.T. Borchardt, Neurochem. Int. 12, 273 (1988), (6) K.T. Finnegan, et al.: Brain. Res. 496, 251 (1989), (7) H. Franke,et al.: Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002) |
| InChi | InChI=1S/C10H12N2O2.BrH/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14 |
| Quantity | 10 mg, 25 mg, 250 mg, Bulk |
