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      5,7-Dihydroxytryptamine hydrobromide

      SKU
      H0026

      Category: API's & Intermediates

      Synonyms
      5,7-DHT , 3-(2-Aminoethyl)-1H-indole-5,7-diol
      31363-74-3 (free b
      CAS-Number
      C10H12N2O2 . HBr
      Molecular Formula
      192.2 . 80.9
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥95% (HPLC)
      Appearance
      Grey-brown powder
      Identity
      1H-NMR

      Properties

      Solvents
      water

      Documentation

      Safety Data Sheet (SDS)
      CDX H0026 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Transportation
      Not dangerous goods
      Description
      Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
      Smiles
      OC1=C(NC=C2CC[NH3+])C2=CC(O)=C1.[Br-]
      InChi Key
      KVRZGCBQKAJSBN-UHFFFAOYSA-N
      References
      (1) H.G. Baumgarten, et al.: Acta Physiol. Scand. Suppl. 391, 1 (1973) , (2) B. Allis & G. Cohen , Eur. J. Pharmacol. 43, 269 (1977) , (3) K. Fuxe, et al.: Ann. N. Y. Acad. Sci. 305, 346 (1978) , (4) M.Z. Wrona, et al.: J. Med. Chem. 29, 499 (1986) , (5) A.K. Sinhababu & R.T. Borchardt , Neurochem. Int. 12, 273 (1988) , (6) K.T. Finnegan, et al.: Brain. Res. 496, 251 (1989) , (7) H. Franke,et al.: Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)
      InChi
      InChI=1S/C10H12N2O2.BrH/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14

      Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.

      SKU: H0026 Category: API's & Intermediates
      • Additional information

      Additional information

      Synonyms

      5,7-DHT, 3-(2-Aminoethyl)-1H-indole-5,7-diol

      Purity

      ≥95% (HPLC)

      Appearance

      Grey-brown powder

      CAS-Number

      31363-74-3 (free b

      Molecular Formula

      C10H12N2O2 . HBr

      Molecular Weight

      192.2 . 80.9

      Identity

      1H-NMR

      Solvents

      water

      Smiles

      OC1=C(NC=C2CC[NH3+])C2=CC(O)=C1.[Br-]

      InChi Key

      KVRZGCBQKAJSBN-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) H.G. Baumgarten, et al.: Acta Physiol. Scand. Suppl. 391, 1 (1973), (2) B. Allis & G. Cohen, Eur. J. Pharmacol. 43, 269 (1977), (3) K. Fuxe, et al.: Ann. N. Y. Acad. Sci. 305, 346 (1978), (4) M.Z. Wrona, et al.: J. Med. Chem. 29, 499 (1986), (5) A.K. Sinhababu & R.T. Borchardt, Neurochem. Int. 12, 273 (1988), (6) K.T. Finnegan, et al.: Brain. Res. 496, 251 (1989), (7) H. Franke,et al.: Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)

      InChi

      InChI=1S/C10H12N2O2.BrH/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14

      Quantity

      10 mg, 25 mg, 250 mg, Bulk

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