Available from stock

6-Chloropurine

SKU: C0684

Category: Building Blocks, Intermediates, Reagents

Synonyms: 6-Chloro-9H-purine; 87-42-3
CAS-Number: C₅H₃ClN₄
Molecular Formula: 154.56
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Light yellow powder
Identity: 1H-NMR

Properties

Solvents: DMSO (20 mg/ml)

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H302
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: 6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.
Smiles: ClC1=C2C(NC=N2)=NC=N1
InChi Key: ZKBQDFAWXLTYKS-UHFFFAOYSA-N
References: (1) A.C. Sartorelli, et al., J. Pharmacol. Exp. Ther. 134, 123 (1961) , (2) J.A. Montgomery & C. Temple, JACS 83, 630 (1961) , (3) M. Fuertes, et al., Tetrahedron 26, 4823 (1970) , (4) I.Y. Hwang, et al., J. Pharmacol. Exp. Ther. 264, 41 (1993) , (5) E. Kierzek & R. Kierzek, Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.23 (2004) , (6) P. Plackova, et al., J. Enzyme Inhib. Med. Chem. 30, 57 (2015) , (7) S. Schwarz, et al., Eur. J. Med. Chem. 90, 595 (2015)
InChi: InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)

6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.

SKU: C0684 Category: Building Blocks, Intermediates, Reagents

Additional information

Additional information

Synonyms	6-Chloro-9H-purine
Purity	≥98% (HPLC)
Appearance	Light yellow powder
CAS-Number	87-42-3
Molecular Formula	C5H3ClN4
Molecular Weight	154.56
Identity	1H-NMR
Solvents	DMSO (20 mg/ml)
Smiles	ClC1=C2C(NC=N2)=NC=N1
InChi Key	ZKBQDFAWXLTYKS-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H302
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) A.C. Sartorelli, et al., J. Pharmacol. Exp. Ther. 134, 123 (1961), (2) J.A. Montgomery & C. Temple, JACS 83, 630 (1961), (3) M. Fuertes, et al., Tetrahedron 26, 4823 (1970), (4) I.Y. Hwang, et al., J. Pharmacol. Exp. Ther. 264, 41 (1993), (5) E. Kierzek & R. Kierzek, Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.23 (2004), (6) P. Plackova, et al., J. Enzyme Inhib. Med. Chem. 30, 57 (2015), (7) S. Schwarz, et al., Eur. J. Med. Chem. 90, 595 (2015)
InChi	InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
Quantity	5 g, 25 g, Bulk