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      6,8-Difluoro-7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid

      SKU
      D0079

      Categories: Fluorescent Detection, Fluorescent Detection

      Synonyms
      Pacific Blue , 6,8-Difluoro-7-hydroxy-3-carboxycoumarin
      215868-31-8
      CAS-Number
      C10H4F2O5
      Molecular Formula
      242.13
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥97% (HPLC)
      Appearance
      Yellow to brown powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO, chloroform

      Documentation

      Safety Data Sheet (SDS)
      CDX D0079 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315-H319-H335
      Precautionary statements
      P261-P305 + P351 + P338
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      Fluorinated fluorescent dye. Increased resistance to photobleaching and higher quantum yields makes it a superior fluorescent dye. Pacific Blue dyes yield conjugates that are strongly fluorescent, even at neutral pH. Spectral data: Extinction 403nm/Emmission 455nm. The amine-reactive succinimidyl ester derivative can be used to create bright blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser.
      Smiles
      FC1=C2C(C=C(C(O)=O)C(O2)=O)=CC(F)=C1O
      InChi Key
      VYNDHICBIRRPFP-UHFFFAOYSA-N
      References
      (1) W.-C. Sun, et al.: Bioorg. Med. Chem. Lett. 8, 3107 (1998) , (2) S.A.E. Marras, et al.: Nucl. Acids Res. 30, e122 (2002)
      InChi
      InChI=1S/C10H4F2O5/c11-5-2-3-1-4(9(14)15)10(16)17-8(3)6(12)7(5)13/h1-2,13H,(H,14,15)

      Fluorinated fluorescent dye. Increased resistance to photobleaching and higher quantum yields makes it a superior fluorescent dye. Pacific Blue dyes yield conjugates that are strongly fluorescent, even at neutral pH. Spectral data: Extinction 403nm/Emmission 455nm. The amine-reactive succinimidyl ester derivative can be used to create bright blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser.

      SKU: D0079 Categories: Fluorescent Detection, Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      Pacific Blue, 6,8-Difluoro-7-hydroxy-3-carboxycoumarin

      Purity

      ≥97% (HPLC)

      Appearance

      Yellow to brown powder

      CAS-Number

      215868-31-8

      Molecular Formula

      C10H4F2O5

      Molecular Weight

      242.13

      Identity

      1H-NMR

      Solvents

      DMSO, chloroform

      Smiles

      FC1=C2C(C=C(C(O)=O)C(O2)=O)=CC(F)=C1O

      InChi Key

      VYNDHICBIRRPFP-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315-H319-H335

      Precautionary statements

      P261-P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) W.-C. Sun, et al.: Bioorg. Med. Chem. Lett. 8, 3107 (1998), (2) S.A.E. Marras, et al.: Nucl. Acids Res. 30, e122 (2002)

      InChi

      InChI=1S/C10H4F2O5/c11-5-2-3-1-4(9(14)15)10(16)17-8(3)6(12)7(5)13/h1-2,13H,(H,14,15)

      Quantity

      10 mg, 50 mg, Bulk

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