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7-Hydroxy-4-methylcoumarin-3-acetic acid

SKU: H0032

Category: Fluorescent Detection

Synonyms: 4-Methylumbelliferone-3-acetic acid, HMCA; 5852-10-8
CAS-Number: C₁₂H₁₀O₅
Molecular Formula: 234.20
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98%
Appearance: Off white to light brown powder
Identity: 1H-NMR

Properties

Solvents: DMSO
Melting Point: 268° C

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315-H319-H335
Precautionary statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: 7-Hydroxy-4-methylcoumarin-3-acetic acid (HMCA) is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin can be used to label peptides, nucleotides and carbohydrates. Can be used as a pH indicator. Spectral Data: λex=360nm; λem=450nm.
Smiles: CC1=C(C(OC2=C1C=CC(O)=C2)=O)CC(O)=O
References: (1) G. Gabor, et al.; Anal. Chim. Acta 313, 131 (1995) , (2) K. Zamojc, et al.; J. Fluoresc. 24, 713 (2014) , (3) K. Zamojc, et al.; Int. J. Mol. Sci. 20, 3802 (2019)
InChi: InChI= 1S/C12H10O5/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4,13H,5H2,1H3,(H,14,15)

7-Hydroxy-4-methylcoumarin-3-acetic acid (HMCA) is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin can be used to label peptides, nucleotides and carbohydrates. Can be used as a pH indicator. Spectral Data: λex=360nm; λem=450nm.

SKU: H0032 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	4-Methylumbelliferone-3-acetic acid, HMCA
Purity	≥98%
Appearance	Off white to light brown powder
CAS-Number	5852-10-8
Molecular Formula	C12H10O5
Molecular Weight	234.20
Identity	1H-NMR
Solvents	DMSO
Melting Point	268° C
Smiles	CC1=C(C(OC2=C1C=CC(O)=C2)=O)CC(O)=O
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315-H319-H335
Precautionary statements	P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) G. Gabor, et al.; Anal. Chim. Acta 313, 131 (1995), (2) K. Zamojc, et al.; J. Fluoresc. 24, 713 (2014), (3) K. Zamojc, et al.; Int. J. Mol. Sci. 20, 3802 (2019)
InChi	InChI= 1S/C12H10O5/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4,13H,5H2,1H3,(H,14,15)
Quantity	1 g, 5 g, Bulk