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    7-Methylguanine

    Available from stock

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      7-Methylguanine

      SKU
      M0082

      Category: Building Blocks, Intermediates, Reagents

      Synonyms
      N7-Methylguanine , NSC 193444 , NSC 19647 , 2-Amino-6-hydroxy-7-methylpurine , Epiguanine
      578-76-7
      CAS-Number
      C6H7N5O
      Molecular Formula
      165.15
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Identity
      1H-NMR
      Appearance
      White powder

      Properties

      Density
      1.83 g/cm3
      Boiling Point
      503.9 °C at 760 mmHg
      Melting Point
      370 °C
      Solvents
      DMSO

      Downloads

      Safety Data Sheet
      CDX M0082 MSDS.pdf
      Shipping
      AMBIENT
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Handling Advice
      Protect from light and moisture.
      Long Term Storage
      -20°C
      Short Term Storage
      +4°C
      Transportation
      Not dangerous goods
      Description
      Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.
      InChi
      InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)
      References
      (1) S.J. Kerr , Tumour Biol. 6, 115 (1985) , (2) C. Hanski & S.J. Kerr , Cell Tissue Res. 241, 203 (1985) , (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009) , (4) J. Fernandez, et al.: Bioorg. Med. Chem. , 18, 6748 (2010)
      InChi Key
      FZWGECJQACGGTI-UHFFFAOYSA-N
      Smiles
      NC(NC1=C2N(C)C=N1)=NC2=O

      Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.

      SKU: M0082 Category: Building Blocks, Intermediates, Reagents
      • Additional information

      Additional information

      Synonyms

      N7-Methylguanine, NSC 193444, NSC 19647, 2-Amino-6-hydroxy-7-methylpurine, Epiguanine

      Purity

      ≥98% (HPLC)

      Appearance

      White powder

      CAS-Number

      578-76-7

      Molecular Formula

      C6H7N5O

      Molecular Weight

      165.15

      Identity

      1H-NMR

      Solvents

      DMSO

      Melting Point

      370 °C

      Boiling Point

      503.9 °C at 760 mmHg

      Density

      1.83 g/cm3

      Smiles

      NC(NC1=C2N(C)C=N1)=NC2=O

      InChi Key

      FZWGECJQACGGTI-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) S.J. Kerr, Tumour Biol. 6, 115 (1985), (2) C. Hanski & S.J. Kerr, Cell Tissue Res. 241, 203 (1985), (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009), (4) J. Fernandez, et al.: Bioorg. Med. Chem., 18, 6748 (2010)

      InChi

      InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)

      Quantity

      250 mg, 500 mg, 1 g, Bulk

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