Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO
- Melting Point
- 370 °C
- Boiling Point
- 503.9 °C at 760 mmHg
- Density
- 1.83 g/cm3
Documentation
- Safety Data Sheet (SDS)
- CDX M0082 MSDS.pdf
Available from stock
7-Methylguanine
- SKU
- M0082
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- N7-Methylguanine , NSC 193444 , NSC 19647 , 2-Amino-6-hydroxy-7-methylpurine , Epiguanine
- 578-76-7
- CAS-Number
- C6H7N5O
- Molecular Formula
- 165.15
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Transportation
- Not dangerous goods
- Description
- Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.
- Smiles
- NC(NC1=C2N(C)C=N1)=NC2=O
- InChi Key
- FZWGECJQACGGTI-UHFFFAOYSA-N
- References
- (1) S.J. Kerr , Tumour Biol. 6, 115 (1985) , (2) C. Hanski & S.J. Kerr , Cell Tissue Res. 241, 203 (1985) , (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009) , (4) J. Fernandez, et al.: Bioorg. Med. Chem. , 18, 6748 (2010)
- InChi
- InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)
Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.
Additional information
| Synonyms | N7-Methylguanine, NSC 193444, NSC 19647, 2-Amino-6-hydroxy-7-methylpurine, Epiguanine |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White powder |
| CAS-Number | 578-76-7 |
| Molecular Formula | C6H7N5O |
| Molecular Weight | 165.15 |
| Identity | 1H-NMR |
| Solvents | DMSO |
| Melting Point | 370 °C |
| Boiling Point | 503.9 °C at 760 mmHg |
| Density | 1.83 g/cm3 |
| Smiles | NC(NC1=C2N(C)C=N1)=NC2=O |
| InChi Key | FZWGECJQACGGTI-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) S.J. Kerr, Tumour Biol. 6, 115 (1985), (2) C. Hanski & S.J. Kerr, Cell Tissue Res. 241, 203 (1985), (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009), (4) J. Fernandez, et al.: Bioorg. Med. Chem., 18, 6748 (2010) |
| InChi | InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12) |
| Quantity | 250 mg, 500 mg, 1 g, Bulk |
