7-Methylguanine

SKU: M0082

Category: Building Blocks, Intermediates, Reagents

Synonyms: N7-Methylguanine , NSC 193444 , NSC 19647 , 2-Amino-6-hydroxy-7-methylpurine , Epiguanine; 578-76-7
CAS-Number: C₆H₇N₅O
Molecular Formula: 165.15
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: 1H-NMR
Appearance: White powder

Properties

Density: 1.83 g/cm3
Boiling Point: 503.9 °C at 760 mmHg
Melting Point: 370 °C
Solvents: DMSO

Downloads

Safety Data Sheet: CDX M0082 MSDS.pdf

Shipping: AMBIENT
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: -20°C
Short Term Storage: +4°C

Transportation: Not dangerous goods

Description: Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.
InChi: InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)
References: (1) S.J. Kerr , Tumour Biol. 6, 115 (1985) , (2) C. Hanski & S.J. Kerr , Cell Tissue Res. 241, 203 (1985) , (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009) , (4) J. Fernandez, et al.: Bioorg. Med. Chem. , 18, 6748 (2010)
InChi Key: FZWGECJQACGGTI-UHFFFAOYSA-N
Smiles: NC(NC1=C2N(C)C=N1)=NC2=O

Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.

SKU: M0082 Category: Building Blocks, Intermediates, Reagents

Additional information

Additional information

Synonyms	N7-Methylguanine, NSC 193444, NSC 19647, 2-Amino-6-hydroxy-7-methylpurine, Epiguanine
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	578-76-7
Molecular Formula	C6H7N5O
Molecular Weight	165.15
Identity	1H-NMR
Solvents	DMSO
Melting Point	370 °C
Boiling Point	503.9 °C at 760 mmHg
Density	1.83 g/cm3
Smiles	NC(NC1=C2N(C)C=N1)=NC2=O
InChi Key	FZWGECJQACGGTI-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) S.J. Kerr, Tumour Biol. 6, 115 (1985), (2) C. Hanski & S.J. Kerr, Cell Tissue Res. 241, 203 (1985), (3) H. Li, et al.: J. Mass. Spectrom. 44, 641 (2009), (4) J. Fernandez, et al.: Bioorg. Med. Chem., 18, 6748 (2010)
InChi	InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)
Quantity	250 mg, 500 mg, 1 g, Bulk