Available from stock

8-Amino-6-methoxyquinoline

SKU: A0655

Category: Building Blocks, Intermediates, Reagents

Synonyms: 6-Methoxy-8-aminoquinoline, Amichin, WR15081, NSC 119507, NSC 119508, NSC 13573; 90-52-8
CAS-Number: C₁₀H₁₀N₂O
Molecular Formula: 174.2
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥95% (NMR)
Appearance: Dark green to dark brown solid
Identity: 1H-NMR

Properties

Solvents: chloroform or DMSO
Melting Point: 41 °C
Boiling Point: 137-138 °C @ Press: 1 Torr

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and air. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H302, H315, H319, H335
Precautionary statements: P261, P271, P280, P302, P304, P305, P313, P332, P337, P338, P340, P351, P352
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: 8-Amino-6-methoxyquinoline is a versatile intermediate or buliding block in medicinal chemistry and analytical research. 8-Amino-6-methoxyquinoline serves as a key intermediate in the synthesis of various pharmaceuticals, particularly antimicrobial, antibacterial, antifungal, antimalarial or neuroprotective substances. It is employed in the development of fluorescent probes for biological imaging, allowing researchers to visualize cellular processes in real-time. It is used as a reagent in various analytical techniques, including chromatography and spectroscopy, to detect and quantify other chemical substances, enhancing the accuracy of analytical results.
Smiles: NC=1C2=C(C=C(OC)C1)C=CC=N2
InChi Key: YGGTVPCTAKYCSQ-UHFFFAOYSA-N
References: (1) T.K. Li & L.J. Magnes, Biochem. Pharmacol. 21, 17 (1972) , (2) F.I. Carroll, et al., J. Med. Chem. 22, 694 (1979) , (3) P.J. Zavala, et al., Talanta 32, 285 (1985) , (4) P. Hochegger, et al., Molecules 26, 5530 (2021)
InChi: InChI=1S/C10H10N2O/c1-13-8-5-7-3-2-4-12-10(7)9(11)6-8/h2-6H,11H2,1H3

8-Amino-6-methoxyquinoline is a versatile intermediate or buliding block in medicinal chemistry and analytical research. 8-Amino-6-methoxyquinoline serves as a key intermediate in the synthesis of various pharmaceuticals, particularly antimicrobial, antibacterial, antifungal, antimalarial or neuroprotective substances. It is employed in the development of fluorescent probes for biological imaging, allowing researchers to visualize cellular processes in real-time. It is used as a reagent in various analytical techniques, including chromatography and spectroscopy, to detect and quantify other chemical substances, enhancing the accuracy of analytical results.

SKU: A0655 Category: Building Blocks, Intermediates, Reagents

Additional information

Additional information

Synonyms	6-Methoxy-8-aminoquinoline, Amichin, WR15081, NSC 119507, NSC 119508, NSC 13573
Purity	≥95% (NMR)
Appearance	Dark green to dark brown solid
CAS-Number	90-52-8
Molecular Formula	C10H10N2O
Molecular Weight	174.2
Identity	1H-NMR
Solvents	chloroform or DMSO
Melting Point	41 °C
Boiling Point	137-138 °C @ Press: 1 Torr
Smiles	NC=1C2=C(C=C(OC)C1)C=CC=N2
InChi Key	YGGTVPCTAKYCSQ-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and air. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H302, H315, H319, H335
Precautionary statements	P261, P271, P280, P302, P304, P305, P313, P332, P337, P338, P340, P351, P352
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) T.K. Li & L.J. Magnes, Biochem. Pharmacol. 21, 17 (1972), (2) F.I. Carroll, et al., J. Med. Chem. 22, 694 (1979), (3) P.J. Zavala, et al., Talanta 32, 285 (1985), (4) P. Hochegger, et al., Molecules 26, 5530 (2021)
InChi	InChI=1S/C10H10N2O/c1-13-8-5-7-3-2-4-12-10(7)9(11)6-8/h2-6H,11H2,1H3
Quantity	1 g, 5 g, Bulk