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    8-Octanoyloxypyrene-1

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      8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt

      SKU
      O0001

      Category: Fluorescent Detection

      Synonyms
      OPTS, Trisodium 8-octanoyloxypyrene-1,3,6-trisulfonate
      115787-84-3
      CAS-Number
      C24H21O11S3 . 3Na
      Molecular Formula
      650.58
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥95% (HPLC)
      Appearance
      Yellow to dark yellow powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMF, DMSO, water or methanol
      Melting Point
      251-260 °C (lit.)
      Fluorescence
      λex 384 nm, λem 409 nm in H2O, λex 460 nm, λem 510 nm in 0.1 M Tris pH 8.0 (esterase)
      Shipping
      AMBIENT
      Short Term Storage
      -20°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315 - H319 - H335
      Precautionary statements
      P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt is a highly polar and water soluble lipase substrate derived from HPTS, which forms tight micelles in aqueous solutions. Lipase activity can be established by measuring the fluorescence kinetics following the increase in emission of HPTS (hydroxypyrene trisulfonic acid). Spectral data: ?ex 384 nm, ?em 409 nm in H2O. Spectral data (esterase cleavage): ?ex 460 nm, ?em 510 nm in 0.1 M Tris pH 8.0.
      Smiles
      [Na+].[Na+].[Na+].CCCCCCCC(=O)Oc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O
      InChi Key
      RZVSWISDVXUSGY-UHFFFAOYSA-K
      References
      (1) B. Baumeister, et al., Org. Lett. 3, 4229 (2001) , (2) Y. Jeong, et al., Chem. Commun. 47, 12077 (2011)
      InChi
      InChI=1S/C24H24O11S3.3Na/c1-2-3-4-5-6-7-22(25)35-18-12-19(36(26,27)28)15-10-11-17-21(38(32,33)34)13-20(37(29,30)31)16-9-8-14(18)23(15)24(16)17,,,/h8-13H,2-7H2,1H3,(H,26,27,28)(H,29,30,31)(H,32,33,34),,,/q,3*+1/p-3

      8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt is a highly polar and water soluble lipase substrate derived from HPTS, which forms tight micelles in aqueous solutions. Lipase activity can be established by measuring the fluorescence kinetics following the increase in emission of HPTS (hydroxypyrene trisulfonic acid). Spectral data: ?ex 384 nm, ?em 409 nm in H2O. Spectral data (esterase cleavage): ?ex 460 nm, ?em 510 nm in 0.1 M Tris pH 8.0.

      SKU: O0001 Category: Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      OPTS, Trisodium 8-octanoyloxypyrene-1,3,6-trisulfonate

      Purity

      ≥95% (HPLC)

      Appearance

      Yellow to dark yellow powder

      CAS-Number

      115787-84-3

      Molecular Formula

      C24H21O11S3 . 3Na

      Molecular Weight

      650.58

      Identity

      1H-NMR

      Solvents

      DMF, DMSO, water or methanol

      Melting Point

      251-260 °C (lit.)

      Fluorescence

      λex 384 nm, λem 409 nm in H2O, λex 460 nm, λem 510 nm in 0.1 M Tris pH 8.0 (esterase)

      Smiles

      [Na+].[Na+].[Na+].CCCCCCCC(=O)Oc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

      InChi Key

      RZVSWISDVXUSGY-UHFFFAOYSA-K

      Shipping

      AMBIENT

      Short Term Storage

      -20°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315 – H319 – H335

      Precautionary statements

      P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) B. Baumeister, et al., Org. Lett. 3, 4229 (2001), (2) Y. Jeong, et al., Chem. Commun. 47, 12077 (2011)

      InChi

      InChI=1S/C24H24O11S3.3Na/c1-2-3-4-5-6-7-22(25)35-18-12-19(36(26,27)28)15-10-11-17-21(38(32,33)34)13-20(37(29,30)31)16-9-8-14(18)23(15)24(16)17,,,/h8-13H,2-7H2,1H3,(H,26,27,28)(H,29,30,31)(H,32,33,34),,,/q,3*+1/p-3

      Quantity

      25 mg, Bulk

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