Specifications
- Purity
- ≥98% (Titration)
- Appearance
- White crystalline powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (50 mg/ml)
- Melting Point
- 192-195 °C (lit.)
Category: Amino Acids, Peptides, Proteins
Major tripeptide widely distributed in both plants and animals. Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Regulates activity of the redox sensitive transcription factor NF-?B. Cytoprotective. Serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. Involved in amino acid transport and maintenance of protein sulfhydryl reduction status. Posseses several metabolic, regulatory and protective functions. Forms disulfide bonds with cysteine residues in proteins.
Synonyms | γ-L-Glutamyl-L-cysteinyl-glycine, GSH |
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Purity | ≥98% (Titration) |
Appearance | White crystalline powder |
CAS-Number | 70-18-8 |
Molecular Formula | C10H17N3O6S |
Molecular Weight | 307.32 |
Identity | 1H-NMR |
Solvents | water (50 mg/ml) |
Melting Point | 192-195 °C (lit.) |
Smiles | OC([C@H](CCC(N[C@@H](CS)C(NCC(O)=O)=O)=O)N)=O |
InChi Key | RWSXRVCMGQZWBV-WDSKDSINSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | A. Pompella, et al., Biochem. Pharmacol. 66, 1499 (2003), A. Pastore, et al., Clin. Chim. Acta. 333, 19 (2003), A. Chatterjee, Nutrients 5, 525 (2013), E.V. Kalinina, et al., Biochemistry 79, 1562 (2014), K. Aquilano, et al., Front. Pharmacol. 5, 196 (2014), P. Diaz-Vivancos, et al., Free Radic. Biol. Med. 89, 1154 (2015), T. Homma & J. Fujii, Curr. Drug Metab. 16, 560 (2015) |
InChi | InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 |
Quantity | 5 g, 25 g, Bulk |