Specifications
- Purity
- ≥98% (NMR)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, methanol, ethanol
- Melting Point
- 160-162 °C (lit.)
Category: Fluorescent Detection, Fluorescent Detection
Tyramine is a naturally-occurring trace amine derived from the amino acid tyrosine that is produced endogenously or can be obtained from certain foods. Tyramine acts as a catecholamine releasing agent. It is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. Acts as a adrenergic and activates trace amine-associated receptor 1. Tyramine also inhibits the release of norepinephrine and dopamine. It is metabolized by monoamine oxidase A. Primarily used as an intermediate in the manufacture of pharmaceutical and agrochemical products.
Synonyms | 2-(4-Hydroxyphenyl)ethylamine, 4-(2-Aminoethyl)phenol, 4-Hydroxyphenethylamine, NSC 249188, p-Tyramine, Uteramine |
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Purity | ≥98% (NMR) |
Appearance | White to off-white powder |
CAS-Number | 51-67-2 |
Molecular Formula | C8H11NO |
Molecular Weight | 137.2 |
Identity | 1H-NMR |
Solvents | DMSO, methanol, ethanol |
Melting Point | 160-162 °C (lit.) |
Smiles | OC1=CC=C(CCN)C=C1 |
InChi Key | DZGWFCGJZKJUFP-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305 + P351 + P338 |
GHS Symbol | GHS07 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) A.J. Gross & I.W. Sizer, J. Biol. Chem.. 234, 1611 (1959), (2) F. Sjoeqvist, Proc. R. Soc. Med. 58, 967 (1965), (3) M. Da Prada, et al., J. Neural. Transm. Suppl. 26, 31 (1988), (4) R.B. Rothman, et al., Science 39, 32 (2001), (5) R. Zucchi, et al., Br. J. Pharmacol. 149, 967 (2006), (6) E.A. Reese, et al., J. Pharmacol. Exp. Therap. 321, 178 (2007), (7) J.J. Maguire, et al., Pharmacol. Rev. 61,1 (2009) |
InChi | InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2 |
Quantity | 5 g, 25 g, Bulk |