Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- 1M ammonium hydroxide (50 mg/ml), DMSO, acetonitrile
- Fluorescence
- λex 375 nm, λem 521 nm (after derivatization with 2-mercaptoethanol)
Available from stock
7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide
- SKU
- F0016
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- 4-Fluoro-7-sulfobenzofurazan
- 91366-65-3
- CAS-Number
- C6H4FN3O3S
- Molecular Formula
- 217.18
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC. ABD-F also reportedly reacts slowly with the hydroxy group of some tyrosine residues as well as amino groups in some proteins, forming products that are nonfluorescent but can be detected by absorbance at 385 nm.
- Smiles
- NS(=O)(=O)C1=CC=C(F)C2=NON=C12
- InChi Key
- XROXHZMRDABMHS-UHFFFAOYSA-N
- References
- (1) R. Karlsson, et al.: Anal. Biochem. 349(1), 136 (2006) , (2) R. B. Thompson et al.: J. Neurosc. Meth. 118(1), 63 (2002) , (3) T. Toyooka, K. Imai et al.: Anal. Chem. 56, 2461 (1984)
- InChi
- InChI=1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)
Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC. ABD-F also reportedly reacts slowly with the hydroxy group of some tyrosine residues as well as amino groups in some proteins, forming products that are nonfluorescent but can be detected by absorbance at 385 nm.
Additional information
| Synonyms | 4-Fluoro-7-sulfobenzofurazan |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to yellow powder |
| CAS-Number | 91366-65-3 |
| Molecular Formula | C6H4FN3O3S |
| Molecular Weight | 217.18 |
| Identity | 1H-NMR |
| Solvents | 1M ammonium hydroxide (50 mg/ml), DMSO, acetonitrile |
| Fluorescence | λex 375 nm, λem 521 nm (after derivatization with 2-mercaptoethanol) |
| Smiles | NS(=O)(=O)C1=CC=C(F)C2=NON=C12 |
| InChi Key | XROXHZMRDABMHS-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) R. Karlsson, et al.: Anal. Biochem. 349(1), 136 (2006), (2) R. B. Thompson et al.: J. Neurosc. Meth. 118(1), 63 (2002), (3) T. Toyooka, K. Imai et al.: Anal. Chem. 56, 2461 (1984) |
| InChi | InChI=1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12) |
| Quantity | 10 mg, Bulk |
