Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder or crystals
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in chloroform, DMSO or methanol.
Documentation
- Safety Data Sheet (SDS)
- CDX A0186 SDS_Vs1.1.pdf
Available from stock
Acetamiprid-d3
- SKU
- A0186
Category: Insecticides
- Synonyms
- d3-Acetamiprid, (E)-N-(6-Chloro-3-pyridylmethyl)-N'-cyano-N-(methyl-d3)acetamidine
- 1353869-35-8
- CAS-Number
- C10D3H8ClN4
- Molecular Formula
- 225.70
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H301,H315,H319,H330,H335
- Precautionary statements
- P260 - P264 - P271 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
- GHS Symbol
- GHS06
- Signal word
- Danger
- RIDADR
- UN2811
- Transportation
- Packing Group II
- Description
- Acetamiprid is a neonicotinoid insecticide that acts as an agonist of insect nicotinic acetylcholine receptors (nAChRs). Formulations containing acetamiprid have been used to control sucking insects on crops and pets. Acetamiprid-d3 is a deuterium-labeled analog of acetamiprid with similar activity. This stable isotope-labeled compound contains three deuterium atoms and is commonly utilized as an internal standard in quantitative analytical methods, including LC-MS/MS and GC-MS assays for pesticide residue detection, environmental monitoring, food safety testing, and pharmacokinetic studies. The isotopic labeling enables accurate correction for sample preparation variability, matrix effects, and instrument fluctuations, improving the precision and reliability of quantitative analyses. Acetamiprid-d3 exhibits physicochemical properties nearly identical to those of the native compound while being readily distinguishable by mass spectrometry.
- Smiles
- ClC1=CC=C(CN(C(C)=NC#N)C([2H])([2H])[2H])C=N1
- InChi Key
- WCXDHFDTOYPNIE-BMSJAHLVSA-N
- References
- (1) M. Tomizawa & J.E. Casida, Annu. Rev. Pharmacol. Toxicol. 45, 247 (2005) (Review) , (2) C. Hao, et al., Rapid Commun. Mass Spectrom. 29, 2225 (2015) , (3) H. Terayama, et al., Int. J. Environ. Health Res. 28, 683 (2018) , (4) L. Zuscikova, et al., Toxics 11, 598 (2023) (Review)
- InChi
- InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3/i2D3
Acetamiprid is a neonicotinoid insecticide that acts as an agonist of insect nicotinic acetylcholine receptors (nAChRs). Formulations containing acetamiprid have been used to control sucking insects on crops and pets. Acetamiprid-d3 is a deuterium-labeled analog of acetamiprid with similar activity. This stable isotope-labeled compound contains three deuterium atoms and is commonly utilized as an internal standard in quantitative analytical methods, including LC-MS/MS and GC-MS assays for pesticide residue detection, environmental monitoring, food safety testing, and pharmacokinetic studies. The isotopic labeling enables accurate correction for sample preparation variability, matrix effects, and instrument fluctuations, improving the precision and reliability of quantitative analyses. Acetamiprid-d3 exhibits physicochemical properties nearly identical to those of the native compound while being readily distinguishable by mass spectrometry.
Additional information
| Synonyms | d3-Acetamiprid, (E)-N-(6-Chloro-3-pyridylmethyl)-N'-cyano-N-(methyl-d3)acetamidine |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder or crystals |
| CAS-Number | 1353869-35-8 |
| Molecular Formula | C10D3H8ClN4 |
| Molecular Weight | 225.70 |
| Identity | 1H-NMR |
| Solvents | Soluble in chloroform, DMSO or methanol. |
| Smiles | ClC1=CC=C(CN(C(C)=NC#N)C([2H])([2H])[2H])C=N1 |
| InChi Key | WCXDHFDTOYPNIE-BMSJAHLVSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H301,H315,H319,H330,H335 |
| Precautionary statements | P260 – P264 – P271 – P302 + P352 – P304 + P340 + P310 – P305 + P351 + P338 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | UN2811 |
| Transportation | Packing Group II |
| References | (1) M. Tomizawa & J.E. Casida, Annu. Rev. Pharmacol. Toxicol. 45, 247 (2005) (Review), (2) C. Hao, et al., Rapid Commun. Mass Spectrom. 29, 2225 (2015), (3) H. Terayama, et al., Int. J. Environ. Health Res. 28, 683 (2018), (4) L. Zuscikova, et al., Toxics 11, 598 (2023) (Review) |
| InChi | InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3/i2D3 |
| Quantity | 10 mg, 50 mg, Bulk |
