Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (10 mg/ml), ethanol (15 mg/ml), methanol, choroform (25 mg/ml)
- Melting Point
- 150-153° C
- Optical Activity
- [α]20/D +76°, c = 0.5 in methanol
Available from stock
Artemisinin
- SKU
- A0335
Category: Antibiotics
- Synonyms
- Arteannuin , Qinghaosu , NSC 369397
- 63968-64-9
- CAS-Number
- C15H22O5
- Molecular Formula
- 282.33
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H242, H400, H410
- Precautionary statements
- P210, P220, P234, P273, P280, P370+P378, P391, P403+P235, P411, P420, and P501
- GHS Symbol
- GHS02+GHS09
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
- Smiles
- CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C_x000D_
- InChi Key
- BLUAFEHZUWYNDE-NNWCWBAJSA-N
- References
- (1) A. Zyad, et al., Phytother. Res. 32, 216 (2018) , (2) E. Konstat-Korzenny, et al., Med. Sci. 6, E19 (2018) , (3) Y. Zhang, et al., Nat. Prod. Bioprospect. 8, 303 (2018) , (4) A. Kumari, et al., Eur. J. Med. Chem. 163, 804 (2019)
Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
Additional information
| Synonyms | Arteannuin, Qinghaosu, NSC 369397 |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | White powder |
| CAS-Number | 63968-64-9 |
| Molecular Formula | C15H22O5 |
| Molecular Weight | 282.33 |
| Identity | 1H-NMR |
| Solvents | DMSO (10 mg/ml), ethanol (15 mg/ml), methanol, choroform (25 mg/ml) |
| Melting Point | 150-153° C |
| Optical Activity | [α]20/D +76°, c = 0.5 in methanol |
| Smiles | CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C_x000D_ |
| InChi Key | BLUAFEHZUWYNDE-NNWCWBAJSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H242, H400, H410 |
| Precautionary statements | P210, P220, P234, P273, P280, P370+P378, P391, P403+P235, P411, P420, and P501 |
| GHS Symbol | GHS02+GHS09 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) A. Zyad, et al., Phytother. Res. 32, 216 (2018), (2) E. Konstat-Korzenny, et al., Med. Sci. 6, E19 (2018), (3) Y. Zhang, et al., Nat. Prod. Bioprospect. 8, 303 (2018), (4) A. Kumari, et al., Eur. J. Med. Chem. 163, 804 (2019) |
| Quantity | 100 mg, Bulk |
