Specifications
- Purity
- ≥99%
- Identity
- 1H-NMR
- Appearance
- White to beige powder
Properties
- Melting Point
- 210 °C (410 °F)
- Solvents
- water (1 g/ml), ethanol (20 mg/ml)
Available from stock
Carbamoylcholine chloride
- SKU
- C0306
Category: API's & Intermediates
- Synonyms
- (2-Hydroxyethyl)trimethylammonium chloride carbamate , Carbachol , Carbamylcholine chloride
- 51-83-2
- CAS-Number
- NH2COOCH2CH2N(Cl)(CH3)3
- Molecular Formula
- 182.65
- Molecular Weight
- Handling Advice
- Very hygroscopic. Store under inert gas.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Long Term Storage
- RT
- Short Term Storage
- RT
- Shipping
- AMBIENT
- Transportation
- Packing Group II
- RIDADR
- 2811 6.1
- Signal word
- Danger
- GHS Symbol
- GHS06
- Precautionary statements
- P264-P301 + P310
- Hazard statements
- H300
- Description
- Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.
- References
- (1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995) , (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003) , (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008) , (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008)
- InChi Key
- AIXAANGOTKPUOY-UHFFFAOYSA-N
- Smiles
- C[N+](C)(C)CCOC(=O)N.[Cl-]
Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.
Additional information
| Synonyms | (2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride |
|---|---|
| Purity | ≥99% |
| Appearance | White to beige powder |
| CAS-Number | 51-83-2 |
| Molecular Formula | NH2COOCH2CH2N(Cl)(CH3)3 |
| Molecular Weight | 182.65 |
| Identity | 1H-NMR |
| Solvents | water (1 g/ml), ethanol (20 mg/ml) |
| Melting Point | 210 °C (410 °F) |
| Smiles | C[N+](C)(C)CCOC(=O)N.[Cl-] |
| InChi Key | AIXAANGOTKPUOY-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Very hygroscopic. Store under inert gas. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Hazard statements | H300 |
| Precautionary statements | P264-P301 + P310 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | 2811 6.1 |
| Transportation | Packing Group II |
| References | (1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995), (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003), (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008), (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008) |
| Quantity | 1 g, 10 g, 25 g, Bulk |
