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    Carbamoylcholine chloride

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    Carbamoylcholine chloride

    SKU
    C0306

    Category: API's & Intermediates

    Synonyms
    (2-Hydroxyethyl)trimethylammonium chloride carbamate , Carbachol , Carbamylcholine chloride
    51-83-2
    CAS-Number
    NH2COOCH2CH2N(Cl)(CH3)3
    Molecular Formula
    182.65
    Molecular Weight

    • Product Data
    • Handling
    • Safety Information
    • Details

    Specifications

    Purity
    ≥99%
    Identity
    1H-NMR
    Appearance
    White to beige powder

    Properties

    Melting Point
    210 °C (410 °F)
    Solvents
    water (1 g/ml), ethanol (20 mg/ml)
    Handling Advice
    Very hygroscopic. Store under inert gas.
    Use / Stability
    Stable for at least 2 years after receipt when stored at RT.
    Long Term Storage
    RT
    Short Term Storage
    RT
    Shipping
    AMBIENT
    Transportation
    Packing Group II
    RIDADR
    2811 6.1
    Signal word
    Danger
    GHS Symbol
    GHS06
    Precautionary statements
    P264-P301 + P310
    Hazard statements
    H300
    Description
    Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.
    References
    (1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995) , (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003) , (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008) , (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008)
    InChi Key
    AIXAANGOTKPUOY-UHFFFAOYSA-N
    Smiles
    C[N+](C)(C)CCOC(=O)N.[Cl-]

    Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.

    SKU: C0306 Category: API's & Intermediates
    • Additional information

    Additional information

    Synonyms

    (2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride

    Purity

    ≥99%

    Appearance

    White to beige powder

    CAS-Number

    51-83-2

    Molecular Formula

    NH2COOCH2CH2N(Cl)(CH3)3

    Molecular Weight

    182.65

    Identity

    1H-NMR

    Solvents

    water (1 g/ml), ethanol (20 mg/ml)

    Melting Point

    210 °C (410 °F)

    Smiles

    C[N+](C)(C)CCOC(=O)N.[Cl-]

    InChi Key

    AIXAANGOTKPUOY-UHFFFAOYSA-N

    Shipping

    AMBIENT

    Short Term Storage

    RT

    Long Term Storage

    RT

    Handling Advice

    Very hygroscopic. Store under inert gas.

    Use / Stability

    Stable for at least 2 years after receipt when stored at RT.

    Hazard statements

    H300

    Precautionary statements

    P264-P301 + P310

    GHS Symbol

    GHS06

    Signal word

    Danger

    RIDADR

    2811 6.1

    Transportation

    Packing Group II

    References

    (1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995), (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003), (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008), (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008)

    Quantity

    1 g, 10 g, 25 g, Bulk

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