Carbamoylcholine chloride

SKU: C0306

Category: API's & Intermediates

Synonyms: (2-Hydroxyethyl)trimethylammonium chloride carbamate , Carbachol , Carbamylcholine chloride; 51-83-2
CAS-Number: NH₂COOCH₂CH₂N(Cl)(CH₃)₃
Molecular Formula: 182.65
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99%
Identity: 1H-NMR
Appearance: White to beige powder

Properties

Melting Point: 210 °C (410 °F)
Solvents: water (1 g/ml), ethanol (20 mg/ml)

Handling Advice: Very hygroscopic. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at RT.
Long Term Storage: RT
Short Term Storage: RT
Shipping: AMBIENT

Transportation: Packing Group II
RIDADR: 2811 6.1
Signal word: Danger
GHS Symbol: GHS06
Precautionary statements: P264-P301 + P310
Hazard statements: H300

Description: Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.
References: (1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995) , (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003) , (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008) , (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008)
InChi Key: AIXAANGOTKPUOY-UHFFFAOYSA-N
Smiles: C[N+](C)(C)CCOC(=O)N.[Cl-]

Non-selective cholinergic agonist that is resistant to the action of cholinesterases, inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes. Carbamoylcholine, also known as carbachol, is an analog of acetylcholine that activates acetylcholine receptors (AChR). Carbamoylcholine is an agonist of both nicotinic (nAChR) and muscarinic (mAChR) receptors.

SKU: C0306 Category: API's & Intermediates

Additional information

Additional information

Synonyms	(2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride
Purity	≥99%
Appearance	White to beige powder
CAS-Number	51-83-2
Molecular Formula	NH2COOCH2CH2N(Cl)(CH3)3
Molecular Weight	182.65
Identity	1H-NMR
Solvents	water (1 g/ml), ethanol (20 mg/ml)
Melting Point	210 °C (410 °F)
Smiles	C[N+](C)(C)CCOC(=O)N.[Cl-]
InChi Key	AIXAANGOTKPUOY-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	RT
Handling Advice	Very hygroscopic. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at RT.
Hazard statements	H300
Precautionary statements	P264-P301 + P310
GHS Symbol	GHS06
Signal word	Danger
RIDADR	2811 6.1
Transportation	Packing Group II
References	(1) G.M. Yan, et al., Mol. Pharmacol. 47, 248 (1995), (2) A.A. Jensen, et al., Mol. Pharmacol. 64, 865 (2003), (3) A.L. Lin, et al., Am. J. Physiol. Cell Physiol. 294, C1454 (2008), (4) D.Y. Xu, et al., Life Sci. 82, 1083 (2008)
Quantity	1 g, 10 g, 25 g, Bulk