• Home
Results for {phrase} ({results_count} of {results_count_total})
Displaying {results_count} results of {results_count_total}

More results...

Filter by Product categories
Bioactive Molecules
Amino Acids, Peptides, Proteins
Carbohydrates
Lipids, Fatty Acids
Metabolites
Phytochemicals
Vitamins
Bioactive Small Molecules
Biopolymers
Detection in Bioanalysis
Fluorescent Detection
Organic Pollutants & Pesticides
Fungicides
Herbicides
Insecticides
Other Pollutants
Pharmaceutically Actives
Antibiotics
API's & Intermediates
Steroids
Reagents and Building Blocks
Reagents for Life Sciences
Buffers
Building Blocks, Intermediates, Reagents
Fluorescent Detection
Linker
Non Fluorescent Detection & Chromogene Detection
Quorum Sensing
Uncategorized
    Industriestrasse 15, CH-9015 St. Gallen, Tel: +41 71 244 48 25
    • 0Shopping Cart
    Chemodex
    • Home
    • Products
    • Catalogs
    • About Chemodex
    • Contact & Distributors
    • Menu Menu
    Cholesterol

    Available from stock

      Inquiry

      Please fill out the form for your inquiry:



      * required field

      Cholesterol

      SKU
      C0249

      Category: Steroids

      Synonyms
      3β-Hydroxy-5-cholestene , 5-Cholesten-3β-ol
      57-88-5
      CAS-Number
      C27H46O
      Molecular Formula
      386.65
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥99%
      Appearance
      White to off-white powder
      Identity
      1H-NMR

      Properties

      Solvents
      chloroform, ether, pyridine, water (insoluble)
      Melting Point
      147-150 °C
      Density
      1.067 g/ml at 25 °C (lit.)

      Documentation

      Safety Data Sheet (SDS)
      CDX C0249 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Transportation
      Not dangerous goods
      Description
      Major component of all biological membranes. Essential structural component of mammalian cell membranes and required to establish proper membrane permeability and fluidity. In addition to its importance within cells, also serves as a precursor for the biosynthesis of steroid hormones, bile acids, and vitamin D. Regulates the function of the transporters and signaling proteins present on the plasma membrane. Implicated in cell signaling processes, assisting in the formation of lipid rafts in the plasma membrane, which brings receptor proteins in close proximity with high concentrations of second messenger molecules. Used to prepare immune-stimulating complexes to enhance cellular and humoral responses and suitable for use in liposome preparations. Binds to and affects the gating of a number of ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel. Also activates the estrogen-related receptor alpha, and may be the endogenous ligand for the receptor. Has been shown to be an important factor in cancer, obesity, neurodeneration and inflammatory diseases.
      Smiles
      CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
      InChi Key
      HVYWMOMLDIMFJA-DPAQBDIFSA-N
      References
      I. Levitan, et al., Front. Physiol. 5, 65 (2014) , J. Zhang & Q. Liu, Protein Cell 6, 254 (2015) , A.R. Tall L. Yvan-Charvet, Nat. Rev. Immunol. 15, 104 (2015) , W. Wei, et al., Cell Metab. 23, 479 (2016) , V. Ribas, et al., Clin. Transl. Med. 5, 22 (2016) , L. Raccosta, et al., Cancer Immunol. Immunother. 65, 111 (2016)
      InChi
      InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

      Major component of all biological membranes. Essential structural component of mammalian cell membranes and required to establish proper membrane permeability and fluidity. In addition to its importance within cells, also serves as a precursor for the biosynthesis of steroid hormones, bile acids, and vitamin D. Regulates the function of the transporters and signaling proteins present on the plasma membrane. Implicated in cell signaling processes, assisting in the formation of lipid rafts in the plasma membrane, which brings receptor proteins in close proximity with high concentrations of second messenger molecules. Used to prepare immune-stimulating complexes to enhance cellular and humoral responses and suitable for use in liposome preparations. Binds to and affects the gating of a number of ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel. Also activates the estrogen-related receptor alpha, and may be the endogenous ligand for the receptor. Has been shown to be an important factor in cancer, obesity, neurodeneration and inflammatory diseases.

      SKU: C0249 Category: Steroids
      • Additional information

      Additional information

      Synonyms

      3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

      Purity

      ≥99%

      Appearance

      White to off-white powder

      CAS-Number

      57-88-5

      Molecular Formula

      C27H46O

      Molecular Weight

      386.65

      Identity

      1H-NMR

      Solvents

      chloroform, ether, pyridine, water (insoluble)

      Melting Point

      147-150 °C

      Density

      1.067 g/ml at 25 °C (lit.)

      Smiles

      CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

      InChi Key

      HVYWMOMLDIMFJA-DPAQBDIFSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      I. Levitan, et al., Front. Physiol. 5, 65 (2014), J. Zhang & Q. Liu, Protein Cell 6, 254 (2015), A.R. Tall L. Yvan-Charvet, Nat. Rev. Immunol. 15, 104 (2015), W. Wei, et al., Cell Metab. 23, 479 (2016), V. Ribas, et al., Clin. Transl. Med. 5, 22 (2016), L. Raccosta, et al., Cancer Immunol. Immunother. 65, 111 (2016)

      InChi

      InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

      Quantity

      25 g, 100 g, Bulk

      Related products

      • 7-Dehydrocholesterol

        7-Dehydrocholesterol

        Purity: ≥95% (HPLC)CAS-Number: 434-16-2SKU: D0331

        Read more Show Details
      • Stigmasterol

        Stigmasterol

        Purity: ≥95% (HPLC)CAS-Number: 83-48-7SKU: S0267

        Read more Show Details
      • Sodium glycochenodeoxycholate

        Sodium glycochenodeoxycholate

        Purity: ≥97% (HPLC)CAS-Number: 16564-43-5SKU: G0033

        Read more Show Details
      • Cholesteryl acetate

        Cholesteryl acetate

        Purity: ≥98% (HPLC)CAS-Number: 604-35-3SKU: C0359

        Read more Show Details
      © Copyright - Chemodex AG - Customized Molecules developed in Switzerland
      • Home
      • All products
      • Order and delivery information
      • Disclaimer
      • Privacy policy
      • About this site
      1,4-Cubanedicarboxylic acid1beta-Cyclodextrinbeta-Cyclodextrin Scroll to top