Clarithromycin N-oxide

SKU: C0310

Category: API's & Intermediates

Synonyms: 6-O-Methylerythromycin N-oxide; 118074-07-0
CAS-Number: C₃₈H₆₉NO₁₄
Molecular Formula: 763.95
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: 1H-NMR
Appearance: White powder

Properties

Solvents: methanol and chloroform

Short Term Storage: +4°C
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: -20°C
Shipping: AMBIENT

Transportation: Not dangerous goods

Description: Biologically incactive urinary metabolite of Clarithromycin (oxidized by ozone), a macrolide antibiotic. Compound can be used as analytical reference material.
InChi: InChI=1S/C38H69NO14/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,48-14)33(53-35-29(41)25(39(11,12)46)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-36(8,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36?,37?,38-/m1/s1
References: (1) S. Ohmori, et al.: Drug Metab. Dispos. 21, 358 (1993) , (2) F. Lange, et al.: Chemosphere 65, 17 (2006)
InChi Key: KDRPFIWYMNONLJ-LNLGJKFZSA-N
Smiles: O=C1[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC([C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)[C@H](C)[C@@H](O[C@H]3[C@H](O)[C@@H]([N+](C)([O-])C)C[C@@H](C)O3)[C@](C)(OC)C[C@H]1C)=O

Biologically incactive urinary metabolite of Clarithromycin (oxidized by ozone), a macrolide antibiotic. Compound can be used as analytical reference material.

SKU: C0310 Category: API's & Intermediates

Additional information

Additional information

Synonyms	6-O-Methylerythromycin N-oxide
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	118074-07-0
Molecular Formula	C38H69NO14
Molecular Weight	763.95
Identity	1H-NMR
Solvents	methanol and chloroform
Smiles	O=C1[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC([C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)[C@H](C)[C@@H](O[C@H]3[C@H](O)[C@@H]([N+](C)([O-])C)C[C@@H](C)O3)[C@](C)(OC)C[C@H]1C)=O
InChi Key	KDRPFIWYMNONLJ-LNLGJKFZSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) S. Ohmori, et al.: Drug Metab. Dispos. 21, 358 (1993), (2) F. Lange, et al.: Chemosphere 65, 17 (2006)
InChi	InChI=1S/C38H69NO14/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,48-14)33(53-35-29(41)25(39(11,12)46)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-36(8,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36?,37?,38-/m1/s1
Quantity	10 mg, 25 mg, 100 mg, Bulk