Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Light yellow powder
Properties
- Solvents
- Soluble in DMSO.
Available from stock
Cnidicin
- SKU
- C0728
Category: Phytochemicals
- Synonyms
- 4,9-bis(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one , Kinidilin , Knidicin
- 14348-21-1
- CAS-Number
- C21H22O5
- Molecular Formula
- 354.40
- Molecular Weight
- Short Term Storage
- +4°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- -20°C
- Shipping
- AMBIENT
- Description
- Cnidicin is a ntural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).
- InChi
- InChI=1S/C21H22O5/c1-13(2)7-10-23-18-15-5-6-17(22)26-20(15)21(25-11-8-14(3)4)19-16(18)9-12-24-19/h5-9,12H,10-11H2,1-4H3
- References
- (1) S.Y. Ryu, et al., Planta Med. 67, 172 (2001) , (2) Y.K. Kim, et al., Phytother. Res. 21, 288 (2007)
- InChi Key
- HJMDOAWWVCOEDW-UHFFFAOYSA-N
- Smiles
- C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3
Cnidicin is a ntural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).
Additional information
| Synonyms | 4,9-bis(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one, Kinidilin, Knidicin |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | Light yellow powder |
| CAS-Number | 14348-21-1 |
| Molecular Formula | C21H22O5 |
| Molecular Weight | 354.40 |
| Identity | 1H-NMR |
| Solvents | Soluble in DMSO. |
| Smiles | C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3 |
| InChi Key | HJMDOAWWVCOEDW-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| References | (1) S.Y. Ryu, et al., Planta Med. 67, 172 (2001), (2) Y.K. Kim, et al., Phytother. Res. 21, 288 (2007) |
| InChi | InChI=1S/C21H22O5/c1-13(2)7-10-23-18-15-5-6-17(22)26-20(15)21(25-11-8-14(3)4)19-16(18)9-12-24-19/h5-9,12H,10-11H2,1-4H3 |
| Quantity | 1 mg, Bulk |
