Specifications
- Purity
- ≥97% (HPLC)
- Identity
- 1H-NMR
- Appearance
- White crystalline powder
Properties
- Boiling Point
- 290-295 °C
- Melting Point
- 166.2-167.3 °C
- Solvents
- water
Available from stock
D-Mannitol
- SKU
- M0228
Category: Carbohydrates
- Synonyms
- Mannite , Osmitrol , Cordycepic acid
- 69-65-8
- CAS-Number
- C6H14O6
- Molecular Formula
- 182.17
- Molecular Weight
- Shipping
- AMBIENT
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- RT
- Short Term Storage
- RT
- Transportation
- Not dangerous goods
- Description
- Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.
- InChi
- InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
- References
- Q. Wang, et al., Drug Metab. Dispos. 36, 2244 (2008) , M. Turina, et al., Inflammation 31, 74 (2008) , A. Nishiyama, et al., J. Nutr. Sci. Vitaminol. 55, 242 (2009) , B.C. Saha & F.M. Racine, Appl. Microbiol. Biotechnol. 89, 879 (2011) , A. Kumar, et al., J. Clin. Diagn. Res. 8, GE01 (2014) , H.L. Ohrem, et al., Pharm. Dev. Technol. 19, 257 (2014) , P. André & F. Villain, Int. J. Cosmet. Sci. (2016)
- InChi Key
- FBPFZTCFMRRESA-KVTDHHQDSA-N
- Smiles
- OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.
Additional information
| Synonyms | Mannite, Osmitrol, Cordycepic acid |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White crystalline powder |
| CAS-Number | 69-65-8 |
| Molecular Formula | C6H14O6 |
| Molecular Weight | 182.17 |
| Identity | 1H-NMR |
| Solvents | water |
| Melting Point | 166.2-167.3 °C |
| Boiling Point | 290-295 °C |
| Smiles | OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O |
| InChi Key | FBPFZTCFMRRESA-KVTDHHQDSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Transportation | Not dangerous goods |
| References | Q. Wang, et al., Drug Metab. Dispos. 36, 2244 (2008), M. Turina, et al., Inflammation 31, 74 (2008), A. Nishiyama, et al., J. Nutr. Sci. Vitaminol. 55, 242 (2009), B.C. Saha & F.M. Racine, Appl. Microbiol. Biotechnol. 89, 879 (2011), A. Kumar, et al., J. Clin. Diagn. Res. 8, GE01 (2014), H.L. Ohrem, et al., Pharm. Dev. Technol. 19, 257 (2014), P. André & F. Villain, Int. J. Cosmet. Sci. (2016) |
| InChi | InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 |
| Quantity | 500 g, Bulk |
