Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- water
- Melting Point
- 88-92 °C (lit.)
- Optical Activity
- [α]20/D -18.0° to -22.0°
Available from stock
D-(-)-Ribose
- SKU
- R0065
Category: Carbohydrates
- Synonyms
- (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal
- 50-69-1
- CAS-Number
- C5H10O5
- Molecular Formula
- 150.13
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Transportation
- Not dangerous goods
- Description
- Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.
- Smiles
- O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O
- InChi Key
- PYMYPHUHKUWMLA-LMVFSUKVSA-N
- References
- L.M. Shecterle, et al., Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010) , P. Addis, et al., J. Diet. Suppl. 9, 178 (2012) , Y. Wei, et al., Biochim. Biophys. Acta 1820, 488 (2012) , N. Minakawa & A. Matsuda, Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014)
- InChi
- InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.
Additional information
| Synonyms | (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 50-69-1 |
| Molecular Formula | C5H10O5 |
| Molecular Weight | 150.13 |
| Identity | 1H-NMR |
| Solvents | water |
| Melting Point | 88-92 °C (lit.) |
| Optical Activity | [α]20/D -18.0° to -22.0° |
| Smiles | O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O |
| InChi Key | PYMYPHUHKUWMLA-LMVFSUKVSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | L.M. Shecterle, et al., Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010), P. Addis, et al., J. Diet. Suppl. 9, 178 (2012), Y. Wei, et al., Biochim. Biophys. Acta 1820, 488 (2012), N. Minakawa & A. Matsuda, Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014) |
| InChi | InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1 |
| Quantity | 25 g, 100 g, 250 g, Bulk |
