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    D-(-)-Ribose

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    D-(-)-Ribose

    SKU
    R0065

    Category: Carbohydrates

    Synonyms
    (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal
    50-69-1
    CAS-Number
    C5H10O5
    Molecular Formula
    150.13
    Molecular Weight

    • Product Data
    • Handling
    • Safety Information
    • Details

    Specifications

    Purity
    ≥98% (HPLC)
    Identity
    1H-NMR
    Appearance
    White to off-white powder

    Properties

    Optical Activity
    [α]20/D -18.0° to -22.0°
    Melting Point
    88-92 °C (lit.)
    Solvents
    water
    Shipping
    AMBIENT
    Use / Stability
    Stable for at least 2 years after receipt when stored at +4°C.
    Handling Advice
    Protect from light and moisture.
    Long Term Storage
    +4°C
    Short Term Storage
    RT
    Transportation
    Not dangerous goods
    Description
    Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.
    InChi
    InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
    References
    L.M. Shecterle, et al., Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010) , P. Addis, et al., J. Diet. Suppl. 9, 178 (2012) , Y. Wei, et al., Biochim. Biophys. Acta 1820, 488 (2012) , N. Minakawa & A. Matsuda, Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014)
    InChi Key
    PYMYPHUHKUWMLA-LMVFSUKVSA-N
    Smiles
    O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O

    Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.

    SKU: R0065 Category: Carbohydrates
    • Additional information

    Additional information

    Synonyms

    (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal

    Purity

    ≥98% (HPLC)

    Appearance

    White to off-white powder

    CAS-Number

    50-69-1

    Molecular Formula

    C5H10O5

    Molecular Weight

    150.13

    Identity

    1H-NMR

    Solvents

    water

    Melting Point

    88-92 °C (lit.)

    Optical Activity

    [α]20/D -18.0° to -22.0°

    Smiles

    O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O

    InChi Key

    PYMYPHUHKUWMLA-LMVFSUKVSA-N

    Shipping

    AMBIENT

    Short Term Storage

    RT

    Long Term Storage

    +4°C

    Handling Advice

    Protect from light and moisture.

    Use / Stability

    Stable for at least 2 years after receipt when stored at +4°C.

    Transportation

    Not dangerous goods

    References

    L.M. Shecterle, et al., Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010), P. Addis, et al., J. Diet. Suppl. 9, 178 (2012), Y. Wei, et al., Biochim. Biophys. Acta 1820, 488 (2012), N. Minakawa & A. Matsuda, Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014)

    InChi

    InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

    Quantity

    25 g, 100 g, 250 g, Bulk

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